Psoriasis and its treatment with ointments
Psoriasis is a widespread pathology, affecting about 2% of the world's inhabitants. Its leading symptom is a monomorphic rash, gradually merging into flat plaques. The difficulty of treating psoriasis lies in its still not fully established origin.
Doctors are inclined to believe that the impetus for the development of the disease is a combination of two factors:
- genetic predisposition;
- disorders of the central and peripheral nervous system.
The next relapse of psoriasis occurs due to an acute experience of a stressful situation, infection with streptococci. For severe disease, doctors use drugs in tablets and injection solutions.
A course of injections or tablets is prescribed in cases where treatment is required not only for an area of the skin, but also for the entire body
And to reduce the pharmacological load on the body, patients are prescribed ointments, gels, and creams. This allows you to significantly reduce the dose of systemic agents. To eliminate mild and moderate symptoms, only ointments are used.
The dosage form has many advantages:
- relative safety, since the ingredients of external agents penetrate into the bloodstream in small quantities;
- targeted, selective impact on inflammatory foci;
- rapid manifestation of the therapeutic effect;
- extremely rare development of systemic adverse reactions;
- the ability to eliminate almost all symptoms in short periods of time.
Patients with mild syndromes or people with a weakened body are prescribed only external treatment.
Many domestic and foreign manufacturers produce one drug in the form of a cream and ointment. The use of the latter is practiced for acute psoriasis. The components of the ointment quickly penetrate into the deepest layers of the skin, preventing damage to healthy cells. And the ingredients from the cream are released slowly, providing a prolonged (long-lasting) effect.
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Review of the drug Dermovate
The drug Dermovate
The drug Dermovate contains a strong glucocorticoid. Be careful when treating psoriasis with this ointment.
Active ingredient (composition)
Clobetasol propionate is a very potent .
Indications for use
Psoriasis (except for extensive vulgar psoriasis and pustular psoriasis), age from 1 year.
Contraindications
Use with caution during breastfeeding and pregnancy.
Duration of therapy
The course is individual, but no more than 4 weeks. If there is no improvement during this period, reconsider therapy.
Side effects
- atrophy on the face - thinning of the skin and dilation of blood vessels, warts;
- pustular form of psoriasis (rare).
Reviews about Dermovate on the forum
Reviews talk about the result of treatment, but there is also an addictive effect. The disease returns after stopping the ointment:
Review of Dermovate ointment by Anastasiya
Medical research
Doctor of Medical Sciences, Professor of the Department of Skin and Venereal Diseases of Moscow State Medical University named after. THEM. Sechenova, A.N. Khlebnikova published a study on treatment with Dermovate ointment:
After 2 weeks treatment with clobetasol propionate cream, there was a regression of skin rashes by 75% in 42.9% of patients, while in the group of patients who used externally chalcinonide cream (class II), this effect occurred only in 15.8% (p < 0.001). After 2 weeks after completion of treatment, relapse was observed in 62.9% of patients treated with chalcinonide, and only in 3.2% of patients treated with clobetasol propionate.
According to the results of the study: Dermovate ointment gives results in the treatment of psoriasis.
Price
The average price in Moscow is 430 rubles. for 25 years
Conclusion about the drug
Dermovate ointment gives results in 42.9% of cases, according to a medical study. Reviews on the forums are positive, but the harm from hormones is also noticeable: as soon as the patient stops using the ointment, psoriasis returns with renewed vigor.
Indications for use
Ointment for psoriasis can be used at any stage of its development. Since the cause of the pathology is not clear, drugs are used in therapy to relieve symptoms.
External agents are included in treatment regimens when the following signs of the disease are detected:
- a single pink or red papule, which is covered with loose silvery-white scales;
- small elements usually formed in places of scratches, injuries and abrasions;
- swollen, hyperemic and itchy plaques;
- bluish tint of the skin, its constant abundant peeling;
- papillomatous and warty growths.
The main task of a cream or ointment for psoriasis is to relieve disease syndromes.
Drugs are often prescribed to adults and children with exudative psoriasis. It is characterized by the formation of crusts and scales on the plaques due to weeping. Treatment of seborrheic pathology affecting the scalp is also indispensable without ointments.
Doctors recommend using products without hormonal components at the first signs of psoriasis. This becomes an excellent prevention of the formation of papules, pustules and plaques on the skin.
Main contraindications
Ointment for psoriasis on the skin is not used if there is an individual intolerance to the active or auxiliary ingredient. Minor hypersensitivity testing is recommended before treatment. Apply a small amount of product (about the size of a pea) to your wrist or elbow. If after an hour the skin does not turn red or swell, then the ointment is absolutely safe.
Before use, it is recommended to conduct a test - apply a little product to areas with thin skin (elbow or wrist). The widest list of contraindications for hormonal ointments. Many of them cannot be used in the following cases:
- pregnancy and breastfeeding;
- the presence of severe pathologies of the liver, kidneys, gastrointestinal tract;
- bacterial, viral, fungal skin diseases;
- malignant and benign neoplasms of any location;
- childhood and sometimes adolescence.
Local preparations are also prohibited from being used if there are microtraumas in the area of papules. These include punctures, cuts, burns, and scratches. If this rule is neglected, the ingredients of ointments and creams will penetrate into the blood in large quantities. In such cases, the risk of systemic side effects increases.
Choice of product
Various ointments and creams are used for psoriasis.
They can be roughly divided into hormonal and non-hormonal. The first ones act clearly and quickly, sharply reducing the intensity of itching and cleansing the skin. The group of non-hormonal drugs for the treatment of psoriasis is popular due to the low risk of complications. They are safer and produce results with long-term use. Hormonal drugs, on the contrary, work quickly, but are more dangerous.
Most non-hormonal topical drugs are considered budgetary.
The specific medication is selected by the doctor. Self-medication worsens the situation and the patient’s well-being.
The advantages of this treatment:
- a targeted effect on the area of altered skin;
- penetration into all layers of the epidermis;
- elimination of unpleasant signs of psoriasis (itching, peeling, general discomfort);
- preventing disease progression.
List of effective ointments for psoriasis
Patients with psoriasis know firsthand how difficult it is to choose a quality product for themselves. Often you have to try more than 10-20 drugs until you find the most effective one.
Doctors take many factors into account when choosing an ointment. This is the form of psoriasis, the stage of its course, the intensity of the symptoms. They focus on the patient’s age and the presence of chronic diseases of internal organs.
When choosing therapy, dermatologists always take into account the patient’s age and the general condition of his body. In the treatment of non-contagious pathologies, two broad groups of local remedies are used:
- hormonal. Contains glucocorticosteroids - synthetic analogues of hormones produced by the adrenal glands;
- non-hormonal. The composition is usually represented by several components with an antiseptic, regenerating, exfoliating effect.
The latter are much safer, but slowly exhibit therapeutic effects. Hormonal drugs have a powerful therapeutic effect, improving skin conditions after the first application. But they cannot be used for a long time due to the high probability of developing adverse reactions.
Hormonal ointments
The kidneys produce hormones in response to the negative effects of external or internal factors. After their release into the blood, inflammation weakens, swelling resolves, and the severity of pain and itching decreases. Their synthetic analogues included in ointments also have all these properties. Such drugs help to improve the well-being of a patient with psoriasis in a few minutes.
Flucinar
Despite the fact that Flucinar was synthesized several decades ago, it is still in great demand in dermatology. The Polish manufacturer produces it in the form of a transparent gel and a denser thick ointment.
The drug exhibits antiexudative, antipruritic, antiallergic and anti-inflammatory effects. Flucinar is prescribed to patients with any form of psoriasis, including those affecting the scalp.
Flucinar is one of the most popular drugs for psoriasis.
Apply a small amount of the drug to previously cleansed skin 2-4 times a day and rub in lightly. The duration of the therapeutic course should not exceed 10 days.
For weakened patients, it is preferable to use the gel. It can be applied in small quantities, reducing the dose of the drug. The cost of Flucinar ointment is about 200 rubles.
Hydrocortisone
This domestically produced medicine is often used in the treatment of psoriasis. Available in the form of a 1% ointment, packaged in aluminum tubes of 10 g. When applied externally, the therapeutic activity of hydrocortisone is due to its antiallergic and antiexudative effect.
In terms of anti-inflammatory activity, Hydrocortisone is 4 times weaker than Prednisolone, which must be taken into account during exacerbation of psoriasis.
The drug is applied in a thin layer to the affected areas of the skin 2-3 times a day. The duration of the therapeutic course depends on the nature of the disease, amounting to about 7-14 days. But if the pathology persists, it is extended to 20 days. Hydrocortisone ointment is cheap - about 25 rubles.
Belosalik
The therapeutic effectiveness of the ointment is determined by its active ingredients. Salicylic acid cleanses the areas where the skin was affected from the scales that have formed. And the glucocorticosteroid betamethasone quickly reduces inflammation, pain and itching.
Belosalik is an effective remedy with several active ingredients
Belosalik is used twice a day. A small amount of ointment is evenly distributed over the surface of the skin, lightly rubbing. For uncomplicated psoriasis, a single application is sufficient. The therapeutic course is 3-4 weeks.
If longer treatment is necessary, Belosalik is used every other day. The cost of the drug is about 200 rubles.
Lorinden A and S
Polish-made products differ somewhat in the composition of active ingredients. The main active ingredient of the drugs is the glucocorticosteroid Flumethasone. Lorinden A also contains salicylic acid, which is characterized by keratolytic and local hypothermic properties. It exfoliates dead skin flakes well and stimulates the formation of young and healthy cells. Therefore, the ointment is prescribed to patients with advanced psoriasis.
In addition to the glucocorticosteroid, Lorinden S contains clioquinol. It inhibits the activity of yeast fungi, dermatophytes, and gram-positive bacteria. Lorinden S is used for psoriasis, the course of which is complicated by a secondary infection.
The products are applied in a thin layer to the affected areas of the skin. At the beginning of treatment, the drug is used up to 3 times a day. When positive dynamics appear - up to 2 times a day. The drug should not be used for more than two weeks. In pharmacies Lorinden A can be purchased for 230 rubles, Lorinden C for 380 rubles.
Sinaflan
Sinaflan ointment, cream, gel and liniment are used to treat psoriasis. The drugs are used to eliminate inflammatory processes, allergic reactions, and itching.
Hormonal agent that quickly relieves irritation and inflammation
Sinaflan copes well with eczema that forms during acute psoriasis at the sites of rashes. The ingredients of the drug penetrate the systemic bloodstream, so it is not prescribed during pregnancy and lactation.
Apply a small amount of the drug to cleansed skin 2-4 times a day and rub in lightly. If necessary, apply a breathable bandage, leaving it on for 3-4 days.
The duration of treatment depends on the nature of the disease and is usually 5-10 days. The doctor can extend the therapeutic course to 3-4 weeks. The price of Sinaflan rarely exceeds 20 rubles.
Non-hormonal ointments
Non-hormonal ointments and creams for psoriasis are much safer than drugs with glucocorticosteroids. Their application to the skin rarely provokes the development of even local adverse reactions.
The use of non-hormonal ointments is the best way to treat chronic psoriasis with mild or moderate symptoms. Disadvantages include a slow therapeutic effect. It appears after several days of treatment after accumulation in the tissues affected by the pathology. So, despite all the benefits of these remedies, you often cannot do without hormonal drugs.
Salicylic
The active ingredient of this ointment is salicylic acid
10% and 20%. Salicylic ointment is available in aluminum tubes or dark glass bottles. In the treatment of psoriasis, it is used as an adjunct during the formation of scales.
The drug has a keratolytic effect, improving skin exfoliation, which has a positive effect on regeneration. Salicylic acid from the ointment is a powerful antiseptic. This chemical compound prevents the penetration of bacteria and fungi into inflammatory foci.
The medicine is applied in a thin layer to the affected surface of the skin 2-3 times a day. Duration of treatment is up to 3 weeks. The cost of Salicylic ointment varies from 15 to 25 rubles, depending on the packaging.
Balsamic liniment according to Vishnevsky
Treatment of psoriasis with these external antiseptic and disinfectants has been practiced for a long time. It is based on birch tar and xeroform, which soothe irritated skin. And castor oil reliably retains the moisture necessary for regeneration.
Liniment according to Vishnevsky is used as an aid. It is used mainly in the treatment of psoriasis localized on the hands and feet.
Tar, on the basis of which “Vishnevsky Ointment” is made, soothes the skin and relieves irritation
Liniment is distributed in a thin layer over the affected areas or a bandage is applied with 5-6 layers of gauze. It is used until the painful symptoms of psoriasis are completely eliminated. In pharmacies, Vishnevsky’s liniment is sold for 30-40 rubles.
Rescuer
The balm contains several natural components that promote a therapeutic effect and recovery for psoriasis. Oil extracts of chamomile and calendula soothe the skin and prevent redness and flaking. Naftalan oil has a resolving and analgesic effect. Lavender essential oil relieves swelling and eliminates irritation. All ingredients used to create the balm are natural, pure, without hormonal and antibiotic agents, which reduces the risk of allergic reactions.
The cost of the drug is about 130 rubles per tube weighing 30 grams. When used, the balm is applied generously to the affected area, which, if necessary, can be covered with a bandage with an insulating layer. Clinical trials revealed no contraindications, which makes the balm safe for use by all groups of people.
https://spasatel-online.ru
Naftaderm
The active ingredient of the ointment is refined naftalan oil. The drug is characterized by an antifungal, softening, absorbable, analgesic, and antiseptic effect on the skin.
In the treatment of psoriasis, it is used to reduce inflammation, accelerate wound healing and eliminate itching. It is not recommended to use Naftaderm for application to the face and scalp.
The product is distributed in a thin layer, without rubbing, onto the affected areas of the skin 2 times a day. The course of treatment is individual and can last from 3 to 4 weeks. To use the drug in children, you should consult your doctor. The cost of Naftaderm varies in various pharmacy chains from 400 to 450 rubles.
Daivonex
This ointment is intended for the treatment of psoriasis at any stage. The main component calcipotriol is an analogue of the natural vitamin D₃ metabolite, which prevents the activation of T-lymphocytes.
The action of Daivonex is based on an analogue of vitamin D₃
Daivonex combines well with almost all drugs used in the treatment of psoriasis. With the exception of those containing salicylic acid. Doctors must take this feature of the external remedy into account when drawing up a treatment regimen.
Daivonex is applied to the affected areas of the skin 2 times a day. The therapeutic effect develops within 1-2 weeks of treatment. The duration of treatment is no more than two months. The price of ointment for psoriasis exceeds 1000 rubles.
Homemade ointments for psoriasis
Ointments prepared according to traditional medicine recipes are not as effective as pharmaceutical preparations. Therefore, it is advisable to use them to prevent painful relapses. Folk remedies are used only after the main treatment to consolidate the achieved result. They cope well with residual itching and quickly eliminate mild discomfort.
How to prepare ointment at home:
- pour a tablespoon of dry string into 0.5 cups of boiling water, leave for a couple of hours, strain. Pour the infusion into a mortar and grind, adding 50 g of lanolin in small portions until it crackles;
- Grind 3 tablespoons of thick honey with a tablespoon of aloe juice in a mortar. Add 2 drops of oil solutions of vitamins A and D and 50 g of baby cream with constant stirring.
The series is a well-known folk anti-inflammatory remedy.
The shelf life of such folk remedies does not exceed 10 days. They should be stored in the refrigerator in an opaque container. The ointment is applied up to 4 times a day until the skin is completely cleared of psoriatic rashes.
Ointments for children
Ointments for psoriasis for children should be not only effective, but also safe. In therapy, predominantly non-hormonal agents are used. But in case of acute relapse of the pathology, glucocorticosteroids are needed to relieve pain and inflammation. In pediatrics, they are used in the lowest possible dosages for a short time.
Kartalin
Kartalin is a non-hormonal drug that is used to treat psoriasis in adults and children. Its composition is represented by solid oil, lysozyme, honey, tripartite, chamomile, vitamin A. Lavender and eucalyptus oils soften and moisturize irritated and reddened skin. And salicylic acid stimulates exfoliation of the upper keratinized layer of the epidermis.
Kartalin contains several active ingredients and is suitable for patients of any age. In pediatrics, Kartalin is usually used from the age of 5, but if necessary, it is also prescribed to younger children.
It is recommended to apply the cream for psoriasis to the affected areas 1-2 times a day. It should not be rubbed in, but only distributed in a thin layer. The therapeutic course in children should not exceed 14 days. The average price of Kartalin in pharmacies is 750 rubles.
Prednisolone
Prednisolone is an effective ointment for psoriasis, although it is relatively inexpensive (14-30 rubles). It is produced by many domestic pharmaceutical factories.
This is a hormonal drug for local and systemic use with an average duration of action. It does not exhibit pronounced steroid activity. It is enough to eliminate the symptoms of psoriasis, but not enough to develop acute adverse reactions.
The drug is applied to the affected areas of the skin of children from 2 years of age in a thin layer up to 3 times a day. If necessary, it is possible to use ointment under occlusive dressings to enhance the effect. Duration of treatment is 5-14 days.
A hormonal agent, which, however, can be used to treat children over 2 years of age
Zinc
This non-hormonal ointment is used in the complex treatment of psoriasis, mainly exudative. Its active ingredient zinc oxide reduces local irritation and inflammation.
The drug has an adsorbing effect and promotes the formation of a protective coating on the skin. Zinc ointment is also characterized by antiseptic, regenerating, and anti-inflammatory properties.
The drug is used externally up to 3 times a day in children over 3 years of age. Usually it is not rubbed in, but spread in a thin layer on psoriatic plaques. The dose and frequency of use depend on the severity of the pathology. An inexpensive but effective product can be bought for 15-30 rubles.
Review of the drug Cloveit
The drug Cloveit
The drug Cloveit gives results in the treatment of psoriatic rashes, but if used incorrectly, there is a high risk of side effects.
Active ingredient (composition)
Clobetasol propionate is a very potent hormone.
Indications for use
Psoriasis in advanced forms can be used from 12 years of age.
Contraindications
- increased sensitivity;
- cannot be used during pregnancy and breastfeeding.
Duration
Individually, no more than 2 weeks. If there is no result, you need to reconsider the treatment and diagnosis. If you need further treatment, you should use drugs with lower strength glucocorticoids.
Side effects
- inhibition of epidermal growth, subcutaneous tissue atrophy;
- dry skin, hypertrichosis or baldness;
- hypo- or hyperpigmentation of the skin;
- perioral dermatitis;
- acne, steroid purpura;
- inflammation of hair follicles, atrophic stripes, secondary infection.
Reviews of Cloveit
There are few reviews. Those who have tried this ointment talk about the consequences:
Review of Cloveit ointment by Guest_Sergey
Review of Cloveit ointment by Rokfeller
Medical research
Research on Cloveit ointment was carried out in Saratov:
Clobetasol propionate (“Cloveit” ointment for external use, Jelfa) is a powerful and very effective topical agent, the use of which in a short course in patients with moderate psoriasis in the stage of progression of dermatosis allows to stabilize the process on the skin and reduce the duration of exacerbation of the disease. The use of clobetasol propionate in a short course during the progression of severe forms of psoriasis is very safe and is not accompanied by subclinical signs of an increase in atrophic phenomena in the skin.
The study shows the effectiveness of the drug. It should be used in a short course.
Price
Price in Moscow - 300 rubles. for 25 years
Conclusions about the drug Cloveit
The use of Cloveit cream gives results in the treatment of psoriasis when used in a short course, always under the strict supervision of a doctor. There are few reviews from people to evaluate, and the medical study does not have specific figures and facts about the effect on psoriasis.
