The entry of parasitic microorganisms into the body causes helminthiasis, which negatively affects health. The drug Vermox, which can destroy many types of parasites, will help eliminate this problem.
The active substance is mebendazole, which prevents helminths from absorbing glucose, which is their food. The worms begin to become exhausted, and after 2 days they die. 1 tablet contains 100 mg of mebendazole and additional substances: magnesium stearate, silicon dioxide, corn starch and talc.
Vermox is available in two forms:
- Tablets - for adults.
- Suspension - for children.
The blister contains 6 tablets. The suspension is sold in glass containers with a volume of 15, 30 and 50 ml. Instructions for use must be included with the medicine.
The drug destroys both adults and larvae.
Rules for taking Vermox
The medicine is intended for use by adult patients and children from 10 years of age, although sometimes an exception is made and is prescribed even from 2 years of age. The dosage varies and depends on the disease.
Apply as follows:
- In the presence of helminthiasis. When the diagnosis is confirmed, treatment begins according to the developed scheme, it depends on the type of parasites. The treatment regimen is designed for maximum effectiveness and a significant reduction in adverse reactions. The daily dose is 1000-3000 mg, divided into 3-4 doses.
- For preventive purposes. To do this, take 1 tablet once. The main thing is that these events should involve the whole family. Periodic intake of one tablet (once every 5 months) will reduce the risk of infection with helminthiasis and other microbial pathologies.
The medicine is not absorbed into the blood, but is excreted in feces and urine.
pharmachologic effect
Vermox tablets are a broad-spectrum anthelmintic drug. Many parasitologists have been using the medicine in their practice for a long time. The main active ingredient is most effective for trichocephalosis. Helminths in the human body stop reproducing and soon die.
The medicine is practically not absorbed in the intestines. The medication is excreted almost unchanged in the feces after 24 hours. Only a small part of the active substance (no more than 10%) is excreted by the kidneys.
How to take Vermox correctly for adults?
Before using the drug Vermox, you should carefully study the instructions included with the medicine.
Features of application:
- When prescribing tablets to diabetics, you need to know that Vermox reduces the need for insulin. This should be taken into account, as hypoglycemia may develop, that is, the sugar level in the blood decreases.
- During the treatment period, alcohol consumption is strictly prohibited.
- With a long course of therapy, it is necessary to constantly monitor the condition of the kidneys and liver.
- It is not advisable to combine the drug Vermox with medications that have the ability to accumulate in the fat layer.
- During therapy with this drug, no special diet or laxatives are required.
- The medicine does not affect psychomotor reactions and concentration.
- After treatment, it is necessary to submit stool for analysis.
You do not need a prescription to purchase the tablets, but it is better to consult your doctor first.
Composition and release form
The pharmaceutical product "Vermazol" is produced in the form of white tablets, placed in contour cells of 6 pieces each or in jars of 6, 12 and 24 pieces. The box with the medicine is accompanied by an insert with a description of the medicine, its contraindications, side effects and method of use. One pill contains 0.1 g of the active ingredient - mebendazole. The additional substances are:
- talc;
- alimentary fiber;
- sodium starch glycolate;
- food additive E954;
- corn starch;
- food additive E572;
- macrogol;
- food emulsifier E551;
- sodium salt of lauryl sulfuric acid.
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Vermox for children
The dose and duration of use depend on the following factors:
- Age.
- Purpose: prevention or treatment.
- Intensity and nature of invasion.
- Type of helminth.
Use of medicine in the treatment of children:
- The medicine is contraindicated for children under 2 years of age, as it has a powerful effect on the child’s fragile immune system.
- If the presence of helminthiasis begins to negatively affect the baby’s health, and other drugs do not work effectively, then Vermox can also be used for one-year-old children.
- The daily pediatric dosage should not exceed 150 mg.
- A convenient form of the drug, a suspension, has been developed specifically for children.
The drug is taken once, and after 10 days the dose is repeated. The dosage and frequency of doses is strictly controlled by a doctor.
When it comes to a child’s health, self-medication is inappropriate.
Contraindications
There are few restrictions on the use of the drug, which distinguishes it from its analogues. This anthelmintic medicine is strictly forbidden to take if you have a stomach ulcer or pancreatic disease.
Other contraindications:
- Liver problems.
- Crohn's disease.
- Intolerance to Vermox ingredients.
- Pregnancy.
- Lactation period.
In addition, Vermox is not prescribed to children under 2 years of age.
Overdose of Vermazole
When using higher doses or longer than the indicated course of treatment, an overdose may occur. It manifests itself in the form of cramps in the abdominal cavity, vomiting, frequent loose stools and severe nausea. There is no special antidote, so it is recommended to rinse the stomach and take Activated Charcoal.
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Analogue tools
If it is impossible to use the anthelmintic drug "Vermazol", its analogues can be prescribed:
Use of the drug Vermox for various diseases
The dosage of Vermox depends on the type of helminthiasis. The active substance of the drug acts on different pathogens in a certain way, so proper diagnosis and the correct treatment regimen are very important. The dosage and duration of taking the drug will depend on the diagnosis.
Standard Application:
In the presence of enterobiasis, adult patients are prescribed a single dose of 1 tablet. To prevent relapse of the disease, the dose can be repeated after 2 weeks.
For the treatment of mixed helminthiasis, ascariasis and taeniasis, the following algorithm is used: 3 days, one tablet in the morning and before bed.
If trichinosis is detected, then take 400 mg three times a day for 3 days, and then for another 7 days, five tablets.
If therapy is prolonged, then the condition of the kidneys and liver must be monitored. After the course of treatment, it is forbidden to drink alcohol, drink laxatives and eat fatty foods for 24 hours.
Indications
The drug can be prescribed by a parasitologist if helminths are detected in the body. Vermox can be taken only after a series of tests. It is impossible to detect the presence of parasites in the body by visual examination. A parasitologist may prescribe stool and blood tests. To detect some types of helminths, tests must be repeated several times.
Indications for the use of Vermox tablets are diseases such as alveococcosis, enterobiasis, gnathostomiasis, ascariasis, capillariasis, hookworm disease, echinococcosis, strongyloidiasis, taeniasis, trichocephalosis, as well as mixed helminthiasis. The type of disease must be determined in order to establish the desired dosage of the drug.
Side effects
Unfortunately, Vermox can cause a number of unwanted effects, although they are quite rare.
The following negative reactions are observed:
- Diarrhea, but also constipation.
- Nausea and urge to vomit.
- Minor pain in the abdominal area.
- The appearance of seizures during sleep.
- Itching and hives.
- Anaphylaxis may develop.
- Neutropenia.
- Exceeding the dose causes baldness.
- Liver transaminases are activated.
- Anemia and dizziness.
Side effects are eliminated with symptomatic therapy.
Contraindications
The medication should never be taken as a preventive measure. Although the medicine is available without a prescription, it should not be used without a doctor’s recommendation. The problem is that Vermox tablets have many contraindications. The drug is not given to children under two years of age. This medicine is considered too toxic for infants.
The drug cannot be prescribed to people who have liver failure or problems with the gastrointestinal tract. Anthelmintic tablets are especially dangerous for patients with an open ulcer.
It is not recommended to take Vermox tablets for people with liver failure or Crohn's disease. In rare cases, hypersensitivity to individual components of the drug may occur. The tablets are contraindicated for use during pregnancy and lactation.
Analogs of the drug Vermox
The most common substitutes include drugs:
- Vormin . The Indian drug can be a good replacement for Vermox. It is available in tablet form and is in the same price category.
- Vermakar . Made in Palestine. They produce tablets and suspensions. It is difficult to find this medicine in Russia and Ukraine; you will have to go to the Republic of Belarus.
- Dekaris . The drug is from a Hungarian manufacturer. It is a relative analogue of Vermox, since its active ingredient is different - levamisole. The medicine has a narrow spectrum of action, but there are fewer side effects. This drug destroys and removes helminths within 24 hours. According to parasitologists, this remedy copes better with nematodes. Experts recommend taking Vermox and Decaris in turn.
- Mebendazole . Produced in China and Latvia. Possessing the same pharmaceutical properties, it costs much less.
- Pyrantel suspension . Produced in India. The suspension is almost non-toxic, so it is often used in the treatment of children from 6 months. The disadvantage is ineffectiveness in prevention.
- Nemozol . Indian tablets are effective against mixed infestations and giardiasis. The active ingredient is albendazole. It is most effective against pork tapeworm and echinococcus larvae. Contraindications for use are hypersensitivity to the ingredients of the drug and damage to the retina.
- Wormil . This remedy is most often prescribed instead of Vermox. Their cost is almost the same, so the choice depends on the doctor and personal considerations.
If you have to use an analogue, you need to take into account the concentration of the active substance and adjust the dosage.
Albendazole as the best anthelmintic
Our readers successfully use Intoxic to get rid of parasites. Seeing how popular this product is, we decided to bring it to your attention. Read more here...
In the world, helminthiases are widespread. Many types of helminths can cause fatal diseases. That is why the pharmaceutical industry annually creates new, more advanced drugs that allow you to get rid of parasites or minimize their toxic effects on the body.
- pharmachologic effect
- Pharmacokinetics
- Indications for use
- Instructions for use
- Contraindications
- special instructions
- Storage of the drug
- Drug price
- Analogs
- Reviews
The most popular drug over the past 20 years has been albendazole (also known as nemozol). This remedy exhibits maximum effect against such parasites as Echinococcus granulosus, Taenia solium and Strongyloides stercolatis. The instructions for use of albendazole have a number of features, therefore, despite positive reviews about the drug, the medicine is taken exclusively as prescribed by a doctor.
pharmachologic effect
Albendazole is a drug used to treat human infection with various types of helminths. The drug is a chemical derivative of benzimidazole carbamate, and is similar in structure to mebendazole.
The principle of action of Nemozol is the selective inhibition of the polymerization process of beta-tubulin. The result is the destruction of the cytoplasmic microtubules of the cells of the digestive system of the worms. The drug leads to irreversible changes in the mechanism of biochemical reactions: the breakdown of glucose is suppressed and the synthesis of ATP molecules is stopped, secretory granules and other organelles of muscle tissue cells stop their movement. All these processes lead to the death of the worms.
Pharmacokinetics
Once in the human digestive system, both albendazole tablets and albendazole suspension are absorbed into the circulatory system in minimal quantities. That is, the medicine has a low level of bioavailability (with the exception of patients suffering from liver damage). In the liver, it is almost immediately transformed into albendazole sulfoxide, which, like the active ingredient of the drug, is characterized by anthelmintic activity. This compound is subsequently converted to albendazole sulfone and other oxidation end products.
Important! Albendazole is distributed to almost all organs and systems of the body. Its traces can be found in the liver tissue, bile, urine, in the walls of the cyst, as well as in the cystic and cerebrospinal fluid. The active substance also gets inside the parasite cysts.
The absorption of the drug can be increased up to 5 times by consuming foods containing large amounts of fat. The maximum concentration of albendazole sulfoxide is achieved 2–5 hours after application. The half-life of the compound is 8–12 hours. In case of liver dysfunction, the concentration of the drug doubles and the half-life becomes longer. The binding of the substance to plasma proteins is 70%. The main part of the active compound leaves the body with bile, the rest in urine. In people with impaired renal function, clearance remains unchanged.
Albendazole acts as an inducer of microsomal enzymes of the cytochrome P-450 (IA) system, and also increases the rate of metabolism of many drugs.
Indications for use
The use of the drug is advisable for neurocysticercosis; echinococcosis of the lungs, liver, peritoneum. The drug is used as part of complex therapy for surgical resection of echonococcal cysts. Albendazole also effectively copes with such types of helminthiases as hookworm disease, necatoriasis, ascariasis, opisthorchiasis, enterobiasis, trichuriasis, microsporidiosis, strongyloidiasis, toxocariasis, giardiasis, mixed helminthiasis.
Effective drugs for the treatment of ascariasis in children
Before starting to use antihelminthic drugs, the child must be shown to a pediatrician or parasitologist. The specialist will not only help you choose the most suitable medicine for the baby, but will also determine the optimal dosage, taking into account the child’s age and the degree of helminthic infestation.
Treating children for roundworms without consulting a doctor is dangerous: an incorrect treatment regimen can lead to the fact that the parasites do not die, but begin to migrate to other internal organs, causing complications. Too high dosages of antiparasitic drugs will have a toxic effect on the child’s body and can provoke the development of adverse reactions.
Before starting to use antihelminthic drugs, the child must be shown to a pediatrician.
How to determine the effect of a drug
After finishing taking Vermox, you must undergo tests to determine the effectiveness of the treatment. To do this, examine the patient's stool for the presence of parasite larvae. If adults, their waste, larvae or eggs are found, the treatment is repeated. In this case, a person can use the same drugs.
If the duration of treatment is prolonged, blood is periodically taken from the patient for study. This is due to the fact that the medicine can change the structure of the blood. The liver is also checked for the same purpose.
A person should not be afraid of how worms come out from Vermox. Moreover, the patient will not feel anything. In most cases, helminths leave the body unnoticed by the owner. This happens on the first day after using the drug. To eliminate the possibility of intestinal obstruction, it is better to do a cleansing enema or take a laxative.
Instructions for use of the medicine
The drug Vermox will help get rid of parasites if you know how to take it correctly. The instructions will inform you about this. In order for the product to remove worms without complications, you should adhere to the correct dosage.
Deworming tablets should be taken within 36 hours. It must be remembered that the dosage may vary. This depends on the type of worms present. If a person does not see the effect of treatment, the dosage should be increased.
A medication may cause adverse events if the patient has the following disorders:
- Diseases of the gastrointestinal tract. In this case, the drug kills the worms, but often the worm does not come out and accumulates in the intestines, causing obstruction, vomiting and diarrhea,
- Liver disorders. The deworming remedy Vermox affects the liver. Therefore, a person may experience yellowing of the skin,
- Frequent migraines and dizziness occur due to malfunctions of the nervous system,
- People prone to allergies experience various swellings and rashes.
Worms in humans quickly die after treatment with Vermox; however, the drug should not be taken if:
- Hypersensitivity,
- Kidney failure.
For preventive purposes, the minimum dosage of the drug should be used.
Vermox can help with enterobiasis after just a single dose. In this case, therapy should be received not only by the person who is diagnosed with the disease, but also by all family members living with him. This is because the disease is very easily transmitted through household items.
It is not surprising that enterobiasis is also called the disease of dirty hands. Therefore, in addition to treatment with medications, strict measures regarding personal hygiene should be established at the source of the disease.
Hand washing should be done after walking, going to the toilet, and before and after eating. All food products must be subjected to heat treatment. Fresh vegetables and fruits must be washed thoroughly, and best of all, doused with boiling water. Personal linen should be changed twice a day, bed linen should be changed at least once a week.
Washing clothes should be done at high water temperature. After washing, the laundry should be ironed well. Elderly and young people should not go to bed in pajamas, since there is a high probability of scratching the perianal area in their sleep, which will lead to the spread of pinworm eggs.
Your home should be constantly wet cleaned, as worm eggs can live in dust and dirt for a long time.
Use in animals
Parasites affect not only people, they also settle in the body of animals. Unlike people, the latter cannot comply with hygienic requirements, so infection most often occurs from them. Having penetrated the body of a pet, helminths begin to multiply and lay eggs, which can get on the animal’s fur. Therefore, doctors insist on regular deworming of dogs and cats living near people.
The composition of Vermox is suitable for the prevention and treatment of animals. The drug is dosed depending on the weight of the pet: for every 10 kg of body weight, 1 g of the drug is prescribed.
Prevention and prognosis
If ascariasis is detected in the early stages and drug therapy is administered in a timely manner, the child is completely free of parasites without any health consequences. The effectiveness of antiparasitic drugs in children is 80-100%.
In the absence of adequate treatment for a long time, the child develops a severe form of helminthic infestation, accompanied by complications and damage to internal organs.
The most effective preventive measure for children of any age is personal hygiene. The child should wash his hands with soap every time before eating, after visiting the street and the toilet, and eat thoroughly peeled raw vegetables and fruits. Preventing the contamination of sandboxes and playgrounds with animal and human feces and regularly loosening the sand also helps to avoid infection with helminths.
Source: https://bolezney.net/vermoks/
