Papaverine suppositories during early pregnancy, why the drug is prescribed and where it is inserted

Only a few women manage to avoid taking pills and medications for the entire nine months. Most of them raise serious concerns, since the effect on the fetus has not been fully studied. Papaverine is prescribed quite often during early pregnancy. Let's consider how to take it correctly, what effect it has on the body of the mother and child, as well as what diseases will be a direct contraindication for treatment.

Papaverine suppositories for uterine tone

Papaverine hydrochloride is an excellent antispasmodic that perfectly relaxes muscles and reduces blood pressure. The medicine papaverine hydrochloride is produced in various forms:

Why is papaverine prescribed during pregnancy?

In any form, papaverine has a positive effect on the body of a pregnant woman; when taken regularly, the following occurs:

Reduced blood pressure
Improving blood supply and relaxing the muscles of the uterus;
The threat of miscarriage associated with uterine hypertonicity is prevented.

It does not harm the health of the unborn child, but on the contrary has a positive effect on him. Several generations of children have already grown up whose mothers took papaverine, and no side effects have been identified on them. Doctors consider it the most universal and most convenient medication to use.

Papaverine can often be prescribed during the first trimester of pregnancy, when other medications are strictly prohibited; suppositories are usually prescribed at this time.

Taking papaverine, a pregnant woman notices that her anxiety stops, she begins to feel much calmer, her heart no longer beats wildly, as its rhythms slow down. But you can take this medicine if your doctor has prescribed it.

Papaverine tablets are usually not prescribed during pregnancy, since they are almost insoluble in aqueous solutions, and only half of the dose taken orally is absorbed into the gastrointestinal tract. Pills do not act as quickly and effectively as injections or rectal suppositories.

What does papaverine contain and how does it work?

Papaverine hydrochloride is a substance that weakens the contraction of muscle fibers located in the walls of internal organs. This hormone is obtained artificially. It was synthesized in the fifties of the 20th century, and all the time it helps women safely bear a child. On its basis, a more effective drug no-spa was created.

It does not affect skeletal muscles, so those taking papaverine do not feel weak. This drug helps reduce uterine spasms and reduces calcium levels in muscle cells. It also helps to relax the walls of blood vessels, which lowers blood pressure.

How are papaverine suppositories used?

When a woman is prescribed suppositories with papaverine during pregnancy, when she buys them, she sees that instructions are attached to them. You need to read it carefully and find out from your doctor all the answers to your questions.

This form of medication is very convenient, as it is easy to administer independently. The suppositories begin to act immediately after dissolution, instantly relieving painful symptoms.

Indications for use

Among the direct indications for the use of Papaverine are:

threat of miscarriage due to uterine hypertonicity. It is this reason that is most often the basis for prescribing Papaverine during pregnancy;
arterial hypertension. Thanks to the drug, the reduction in high blood pressure occurs gently, without creating a threat to the fetus;
colic of various types (intestinal, renal, hepatic). In this case, the substance relaxes the excretory ducts that have undergone spasms, restoring the natural functions of the organ and relieving pain;
bronchospasm. Thanks to the action of the drug, the smooth muscles of the respiratory tract relax and normal respiratory function is quickly restored;
presence of high body temperature. In this case, papaverine can be used as part of a lytic mixture.

If during pregnancy you experience abdominal pain for 24 hours, immediately seek advice from a doctor, do not hesitate to ask him the most ridiculous questions in order to have all the necessary information about your condition.

At what stages of pregnancy is the drug used?

It is important to note that the instructions for use of the drug Papaverine do not contain information confirming the safety of its use during pregnancy. There is information about its penetration into the systemic bloodstream, so the decision on prescribing should be made by the doctor, comparing the expected benefits with the risks present.

In the early stages of pregnancy (in the 1st and 2nd trimester), the drug is used to prevent spontaneous abortion. In the third trimester, with increased tone, the medication is used to avoid premature birth. Papaverine is used to prepare the cervix starting from the 40th week of pregnancy, if this process is not provided naturally by the woman’s body. In some cases, the medication is used to relieve pain during contractions during childbirth.

Despite the absence of specific information about the possibility of using the drug during pregnancy in the original instructions, gynecologists prescribe Papaverine to their patients. Long-term practice of use is successful, the product does not provoke the appearance of pathologies of intrauterine development and other problems, newborns are born developed and healthy.

Based on this information, we can conclude that Papaverine is often used in gynecological practice. The medication helps a woman bear and give birth to a healthy child in a timely manner. For the same purpose, doctors recommend that women use No-shpa, but there are contraindications to its use in the 3rd trimester.

Reviews from women

At my first appointment, the doctor told me that suppositories with papaverine are my friend for the entire pregnancy. As soon as I felt that my stomach was full after a day of work, cleaning the apartment or after examinations by a gynecologist, I immediately put them on.

kisyush@ https://www.u-mama.ru/forum/waiting-baby/pregnancy-and-childbirth/269971/index.html

I personally experienced them myself. I put them on consistently from 5 weeks to 9 (all the time in the morning and evening). After a five-day break, I woke up at night from a sharp pain in my stomach. I could barely reach the papaverine candles. It went away 5-7 minutes after taking it.

kozjavohka https://www.u-mama.ru/forum/waiting-baby/pregnancy-and-childbirth/269971/index.html

In the first trimester of pregnancy, I was diagnosed with threatened miscarriage. They prescribed Papaverine hydrochloride suppositories. I took them every day at night. The action of papaverine begins almost five minutes after administration. Almost always after use, blood pressure decreased. Sometimes it was so strong that I had to lie down for several hours after taking the suppositories. I think it’s a plus that suppositories with papaverine help in complex treatment to remove the diagnosis of “threat”.

ek9345 https://otzovik.com/review_1357179.html

I purchased Papaverine Hydrochloride suppositories at a pharmacy on the advice of a doctor in the early stages of pregnancy to improve the condition and relieve slight tone of the uterus. But that was not the case. The medicine was a C grade, because with my problems, albeit to a lesser extent, I had to continue to suffer for the rest of my pregnancy. It helps one, but not another.

dawn https://otzovik.com/review_919865.html

Both of my pregnancies were “threatened”, and each time I was additionally prescribed Papaverine suppositories. Papaverine suppositories relieve tone, that is, relax the smooth muscles of the uterus. For me there was one big disadvantage when using candles. They melted inside and flowed out.

Tin-ka https://otzovik.com/review_1352089.html

I first became acquainted with Papaverine suppositories during pregnancy. At 18 weeks, uterine tone suddenly appeared, as well as periodic abdominal pain. Papaverine suppositories were my salvation. They are safe and really help.

Ekaterinka 224 https://irecommend.ru/content/prinimala-vo-vremya-beremennosti-i-chtoby-vyzvat-rod y

Papaverine for uterine tone, how to take it, are there any contraindications?

Uterine tone is a dangerous condition for a pregnant woman. This phenomenon can lead to premature birth, miscarriage and even fetal death. Unfortunately, spasms occur quite often during pregnancy.

To prevent the negative consequences of tone, patients are prescribed medications to reduce uterine spasms. The article will talk about Papaverine.

We will look at whether it can be taken and what effect it has on the body.

The photo shows the state of hypertonicity of the organ during pregnancy.

Is it possible to take papaverine for uterine tone?

If a woman's uterus is in a state of spasm, it urgently needs to be eliminated. Is it possible to take Papaverine for this?

Papaverine is an antispasmodic drug whose active substance is papaverine hydrochloride. It is quite often prescribed to pregnant women. It is believed that the drug does not affect the baby in any way and does not expose him to miscarriage.

In fact, its 100% effectiveness in uterine tone has not been proven. However, the fact that it is prescribed to pregnant women and that it really helps many people suggests that the drug can be taken for spasms.

Rules for taking for uterine tone

Of course, all medications should be taken with caution. And especially during pregnancy

He has rules that the patient must follow so as not to harm either herself or the baby.

Papaverine tablets. Usually prescribed to women in late pregnancy to relieve tone and prevent premature birth. The dose is to take a tablet 3-4 times a day. The duration of taking the medicine is determined by the doctor. You must strictly follow the instructions so as not to harm the baby.
Papaverine in suppositories is prescribed to girls who are in the first trimester of pregnancy. Usually, for tone, 2-3 suppositories are prescribed during the day.

At later stages, before the birth itself, injections are used if it is necessary to relax the uterus.

During pregnancy, the patient's hormone progesterone is elevated. This hormone itself suppresses spasms in the uterus. He is responsible for the safety of the child from premature birth and miscarriages. But for various reasons, the amount of hormones in the blood can become low. This entails a number of problems. In this case, the body needs help.

As we have already discussed, Papaverine is an antispasmodic. Drugs in this group are aimed at relaxing muscles. The medicine has a relaxing effect on the organ and, as a result, relieves spasm. Thus, the woman comes out of the state of hypertonicity and the baby is not in danger.

Indications and contraindications

Who is Papaverine intended for? For those who have the following diseases and abnormalities:

Spasm of the abdominal muscles (cholecystitis, renal colic, spastic colitis, etc.);
Vasospasm (endarteritis);
Spasm of cerebral vessels;
Angina;
Bronchial spasm;
Uterine tone.

However, there are those who should not use Papaverine under any circumstances:

People with individual intolerance;
Those with AV block;
People with glaucoma;
Those with impaired liver function;
Elderly people due to the high likelihood of hyperthermia;
Children up to six months old.

This drug has so-called relative contraindications

That is, some people should take it with extreme caution. For example, for those who:

There was a traumatic brain injury;
Hypothyroidism;
The functioning of the adrenal glands is disrupted;
State of shock;
Diseased prostate gland;
Supraventricular tachycardia.

Side effects

In order to reduce the likelihood of side effects, a woman must follow a number of rules:

Avoid sexual contact so as not to provoke excessive muscle spasm;
Do not smoke, as tobacco reduces the beneficial effect of the drug taken;
Eat properly;
Walk a lot.

However, despite all these actions, a woman may experience side effects from taking the medicine:

Allergy to the drug;
Reduced blood pressure;
Eosinophilia;
AV block (delay or complete cessation of the passage of impulses through the AV node, legs and bundle of His to the ventricles);
Constipation;
Constant weakness and drowsiness;
Ventricular extrasystole.

When taken together with dopegit, Papaverine reduces the effect of the latter.

So, if a girl suffers from uterine tone, this phenomenon cannot be ignored. The doctor will definitely prescribe a medicine to relieve spasm. Follow the recommendations so as not to harm yourself and your baby.

Usage algorithm

The advantages of the drug include its ease of use. After carefully reading the instructions, you can light the candles yourself. They are intended for rectal use.

Store the suppositories in the refrigerator to make them easier to administer.

Suppositories are used as follows:

When starting the procedure, disinfect your hands or wear sterile gloves.
Take a comfortable position (lying on your side or back).
Gently insert the suppository into the anus, pushing it through the anus.

The dosage of the medicine is prescribed by the gynecologist. Most often, 20 mg of the drug is administered once three times a day with a break of 4 hours. Duration of use is about three weeks.

The prescribed course may vary depending on the patient’s well-being at the discretion of the doctor, who adjusts the duration of therapeutic use based on the existing symptoms and the period of pregnancy.

Absorption of the substance into the blood occurs in a short period. If it is necessary to quickly remove it, hemodialysis is used.

During my first pregnancy, at 3 months, I started having abdominal pain, and the gynecologist decided to hospitalize me. I had to stay in the hospital for three weeks due to uterine hypertonicity. I was prescribed Papaverine suppositories at night. The condition improved quite quickly. These suppositories relieved muscle tension and helped save the child. The pregnancy ended well. Now my son is already 12 years old.

Method of using Papaverine suppositories

The drug is also prescribed to children and the elderly.

Use at different stages of pregnancy

2. From the 13th week of pregnancy, the list of approved drugs increases. To reduce the tone of the uterus, more serious medications are used (Ginipral, Bricanil, Magnesia, etc.), which relax the smooth muscles. With the help of papaverine suppositories, pain and spasm are eliminated in the following diseases: renal colic, diseases of the digestive tract, and genitourinary system. The drug is also used to normalize blood pressure.

• High uterine tone long before birth. Suppositories are taken together with steroid hormones.

• Suppositories are used before labor to detect true contractions. If after insertion of the suppository the uterus continues to contract, it means that labor has already begun.

• Using the drug, the uterus is prepared for the upcoming birth at 38–39 weeks. Suppositories soften the cervix.

• Papaverine suppositories during childbirth reduce pain.

The duration of the therapeutic course depends on the symptoms, stage of pregnancy and is determined solely by the attending physician.

Symptoms and consequences of increased uterine tone

The main symptom of uterine hypertonicity in the early stages is nagging pain in the lower abdomen (as during menstruation), pain in the lower back and in the sacral area. In the second trimester and later, there are cramping pains and hardening of the abdomen, which is clearly felt when palpating it.

The increased tone of the uterus in the early stages is aggravated by spotting blood from the genital tract. Then there is a risk of spontaneous miscarriage, since it is difficult for the fertilized egg to attach to the wall of the uterus due to the increased tone of the muscular layer of the uterus.

In the second trimester of pregnancy, when the placenta has already fully formed, there is a risk of its detachment due to increased uterine tone.

In the later stages of pregnancy, hypertonicity of the uterus can lead to premature birth, because such contraction of the uterus occurs during labor to help the baby be born.

Also, a negative consequence of uterine hypertonicity is fetal hypoxia, when the uteroplacental blood flow is disrupted due to the tone of the muscular layer of the uterus. Thus, the fetus receives insufficient amounts of oxygen and nutrients necessary for its normal development. Typically, such a fetus lags behind in weight and size, its development is also slowed down, and if treatment is not timely, malformations of the fetal organs may develop, or even this may lead to a missed abortion, i.e. to the death of the fetus.

Suppositories with papaverine during pregnancy

While carrying a baby, the expectant mother tries with special care to protect herself from all sorts of negative factors that can cause pregnancy complications. These include any diseases, painful conditions, or stressful situations that pose a certain threat to bearing a baby. And yet, sometimes, despite all the efforts of a pregnant woman, it happens that such conditions still overtake her. Some of them require the use of medications to correct them, which makes the expectant mother even more worried.

It is known that the pregnancy period should, if possible, exclude the use of any medications - in order to avoid negative consequences for the pregnancy itself and the rapidly developing baby. However, there are medications that have been tested by time and experience, which, if necessary, can only benefit the mother and alleviate certain conditions, without harming the baby in any way. One of these remedies is papaverine: an antispasmodic drug that relaxes and eliminates painful conditions.

Papaverine today can be found in the form of tablets, rectal suppositories, and injection solution. However, during pregnancy, in most cases, suppositories with papaverine are prescribed. This universal and easy-to-use remedy can save the expectant mother from many misfortunes that threaten pregnancy. For example, the most common use of a suppository with papaverine during pregnancy is if a woman has a condition such as uterine hypertonicity.

With hypertonicity, the muscles of the uterus, which is the “house” of the baby, are in constant tension, which is fraught with premature termination of pregnancy. In order to avoid miscarriage, it is necessary to relax the muscles of the uterus and give the baby the opportunity to develop without risks. Suppositories with papaverine during pregnancy can cope with uterine hypertonicity, since this medicine has a pronounced antispasmodic effect: suppositories lower blood pressure and relieve tension in the smooth muscles of internal organs. In addition, with regular use of suppositories, a slight sedative effect is felt: the woman becomes calmer, and even the heart rate slows down: the heart stops pounding and causing anxiety.

Despite the fact that many sources indicate that it is supposedly undesirable to use papaverine when carrying a child, however, the long-term use of this medicine indicates exactly the opposite. Almost all mothers who used suppositories with papaverine during pregnancy carried them to term and gave birth to strong babies without any negative consequences. Many years of experience in using papaverine proves that suppositories with papaverine have absolutely no effect on the baby, and at the same time neutralize the threat of involuntary abortion associated with uterine hypertonicity. The only thing is that suppositories with papaverine during pregnancy in some individual cases can cause individual side effects in the mother. Among them are nausea, drowsiness, increased sweating, and constipation. The use of suppositories can provoke allergic reactions or a drop in blood pressure - but all this is only in isolated cases. In general, suppositories with papaverine during pregnancy are tolerated relatively easily, and can even be used for quite a long time.

Despite the fact that suppositories do not pose a threat to the fetus, self-medication is not permissible: suppositories with papaverine should be used during pregnancy only after consultation with a doctor, who determines the dosage. As a rule, suppositories are prescribed at the rate of 2-3 suppositories per day at equal intervals. The form of the drug is convenient to use: women can administer suppositories with papaverine during pregnancy on their own, and they begin to act almost immediately after dissolution. Contraindications to the use of suppositories with papaverine during pregnancy include problems with the expectant mother's liver, tachycardia, increased intraocular pressure, and thyroid dysfunction.

Contraindications

Although the drug is safe for a child who is developing in the uterus, its use is unacceptable for certain pathologies and health problems in the expectant mother.

Treatment with Papaverine is prohibited if a woman:

hypersensitivity to any ingredient of the drug has been detected;
liver function is seriously impaired;
atrioventricular block was diagnosed;
Glaucoma was detected.

For severe diseases of the kidneys, thyroid gland, heart and other organs, this medication can only be used under the supervision of a specialist. He must examine the pregnant woman and make sure that taking Papaverine in the presence of such concomitant diseases is justified.

Causes and methods of diagnosing uterine hypertonicity

There are many reasons for the appearance of increased uterine tone during pregnancy:

hormonal deficiency;
diseases of the uterus (inflammatory processes of the appendages and the uterus itself, endometriosis, uterine fibroids, etc.) and disruption of the central nervous system;
exacerbation of chronic diseases and the occurrence of colds (acute respiratory infections, acute respiratory viral infections and other ailments characterized by an increase in body temperature);
constant stress and increased physical activity, insufficient sleep and/or rest, as well as the presence of bad habits in the pregnant woman;
polyhydramnios, multiple births or large fetus.

Local hypertonicity of the uterus along the posterior or anterior wall can be determined using ultrasound. At the same time, an ultrasound shows a change in the wall of the uterus at the site of its tone; it bends inward.

There is also a special sensor for determining the tone of the uterus. But, unfortunately, tonuometry is not carried out in all antenatal clinics.

Characteristics of the drug

Papaverine suppositories or Papaverine hydrochloride belong to the antispasmodic group of drugs, the purpose of which is to relax smooth muscle cells. Its effect is on all systems and organs of the human body that contain smooth muscles, including blood vessels. This particular drug is one of the few drugs that are so often used during pregnancy. Read more about pregnancy management→

Papaverine or Papaverine hydrochloride suppositories are administered rectally during pregnancy, and the drug does not have any negative effect on the fetus, but, on the contrary, helps maintain pregnancy when there is a threat of termination, since it perfectly reduces the increased tone of the uterus and blood flow in the placental-uterine circle.

The main effect of the drug is aimed at:

reduction of muscle tension and relaxation of the muscles of internal organs;
improved blood circulation in soft muscles, especially in the muscles of the uterus;
decrease in blood pressure with its sharp increase;
stabilization of heart rate.

The drug is available in three forms:

pills;
solutions for injection (intravenous, intramuscular, subcutaneous);
rectal suppositories.

Features of use at different stages of pregnancy

The regimen for taking the drug Papaverine during pregnancy is determined by the attending physician. When prescribing a medication, the doctor takes into account the patient’s gestational age and the nature of the pathological process. The duration of use is also determined individually. In the case of uterine tone, the drug is discontinued as it is eliminated.

Some women think that with uterine tone, only intravaginal drugs can be used, so they have a question about where to insert the suppository. It should be borne in mind that Papaverine vaginal suppositories do not exist. The medicine is intended for rectal use. With accidental, one-time vaginal administration, there is no danger to the fetus, the drug is not able to influence the development of the baby in the womb. With constant violation of application technology, the risk of microflora disorders in a woman increases.

First trimester of pregnancy

Papaverine in the form of rectal suppositories is often prescribed to women in early pregnancy, in the first trimester, when there is a threat of spontaneous abortion. The product must not be used independently, without a doctor’s prescription; self-medication can lead to irreversible consequences.

If a threat of spontaneous abortion is detected, the drug is prescribed in injection form. The drug is used in a hospital setting, the drug is administered by drip or injection into a vein. The advantage of this form of release is the sufficient speed of obtaining a therapeutic result.

Second trimester of pregnancy

The second trimester of pregnancy begins at 14 weeks and most women believe that the risk of miscarriage has been completely eliminated by this point, but this opinion cannot be called correct. Stress can still provoke a miscarriage at this stage of gestation.

Increased tone is manifested by involuntary contractions of the uterus at intervals of several seconds. Particular danger appears if spotting is added to the condition. In this case, women are recommended to take the drug orally and use rectal suppositories. The condition is not always an indication for hospitalization.

Third trimester of pregnancy

In the third trimester, Papaverine suppositories are also recommended for uterine hypertonicity. Their use will prevent premature birth. Injection is not used at this stage of gestation.

Attention! The drug Papaverine is used before childbirth to reduce pain accompanying contractions. In the 3rd trimester, Papaverine is used to stimulate the intensity of cervical dilatation, if this condition is not provided by the body naturally

The drug may relax the cervix. To stimulate labor, suppositories are used in a dose of 1 suppository rectally 4 times a day. Duration of use is determined individually

In the 3rd trimester, Papaverine is used to stimulate the intensity of cervical dilatation if this condition is not provided by the body naturally. The drug may relax the cervix. To stimulate labor, suppositories are used in a dose of 1 suppository rectally 4 times a day. The duration of use is determined individually.

Papaverine is a myotropic antispasmodic intended to lower blood pressure and reduce heart rate. The drug acts on the muscles and is able to eliminate spasms of various origins; it is due to this feature that it is used in gynecological practice. The need to use the product is determined by a gynecologist, and the drug is prescribed for different periods.

List of indications for use in gynecology

The drug is prescribed to pregnant women when the following indications for use are identified:

high blood pressure;
disruption of the blood supply to the pelvic organs;
spasms of the smooth muscles of the uterus;
hepatic, bronchial and renal colic;
bronchospasm that interferes with normal breathing.

In gynecological practice, Papaverine is used in different dosage forms:

pills;
solution for injection;
rectal suppositories.

During pregnancy, women are rarely prescribed the drug in tablet form. This is due to the fact that with active hypertonicity of the uterus, a woman needs emergency care, and the pills act rather slowly.

Injection form

The injection form is a priority for use during pregnancy. Immediately after administration of the drug intravenously, the drug enters the systemic bloodstream, the effect is observed instantly. The effect of intramuscular administration occurs later.

Most often, the drug in injection form is used in a hospital setting, after a woman has been diagnosed with a threat of premature termination of pregnancy. You need to pay attention to the specifics of administering the medicine; you need to inject it very slowly so that the medicine gradually enters the bloodstream.

It is quite difficult to give an injection intravenously or intramuscularly on your own; it must be done by a doctor or nurse. After the active substance enters the bloodstream, the woman’s condition returns to normal within a few minutes. The effect of the drug is noticeable by reducing the heart rate. Frequency of use – up to 4 times a day.

Attention! The therapeutic effect of using Papaverine manifests itself quickly, so the composition is used to relieve emergency conditions.

Suppositories with Papaverine during pregnancy

If the tone of the uterus is insignificant, the woman does not require hospitalization. In the early stages, rectal suppositories Papaverine provide its elimination. Suppositories are often used for home treatment; they maintain the normal condition of the uterus. Absorption occurs quickly, the woman feels a noticeable improvement in well-being a few minutes after inserting the suppository into the rectum.

When inserting a suppository, you must follow the instructions for use:

Hands should be washed with antibacterial soap and dried with a clean towel or disposable napkin.
Remove the suppository from the package, lie on your side, slightly raise the leg on top.
Insert the suppository into the anus and remain in a horizontal position for 10 minutes so that the suppository has time to completely dissolve in the rectum.

If there is a threat of spontaneous abortion, doctors recommend using the drug 2-3 times a day. The duration of treatment is 2-3 weeks, depending on the results.

Pills

Doctors do not recommend using papaverine in tablets for the cervix. The therapeutic effect of the composition appears 40-60 minutes after oral administration, and in the case of a threat of miscarriage, you cannot hesitate to eliminate the spasm. Prolonged preservation of tone can cause pathologies in fetal development or miscarriage. You can use tablets if there are no other medications available.

Attention! If there is a suspicion of increased uterine tone, a woman should consult a gynecologist as an emergency; self-medication is unacceptable. Papaverine is rarely used on an ongoing basis; to reduce the risk of miscarriage, doctors prescribe drugs containing progesterone.

Possible contraindications and side effects

The instructions for the use of suppositories with papaverine say that their use is contraindicated if the patient’s medical history contains records of:

heart rhythm disorder caused by impaired AV conduction; increased intraocular pressure (glaucoma); liver, kidney failure, adrenal dysfunction (with caution); violation of bronchial obstruction; inflammation of the rectum.

In addition, a woman’s body during pregnancy can react in an unexpected way even to a familiar and safe drug. Therefore, known or identified intolerance to the components of papaverine suppositories is also considered a contraindication to their use.

More serious consequences may occur due to exceeding the prescribed dose: severe sedation, cardiac dysfunction, difficulty urinating and defecating, hypotension, dizziness, etc.

Side effects from taking papaverine

Like any medicine, regardless of the form of release, the drug “Papaverine” can also have a negative effect on the body of the expectant mother. Possible side effects include:

allergies,
pressure reduction,
constipation,
drowsiness,
nausea,
dizziness,
increased sweating;
heart rhythm disturbance.

Heart failure occurs most often due to rapid intravenous or intramuscular administration. But the remaining effects can be obtained by the mother who independently increases the recommended dose.

Action and release form

Papaverine is the name of a medicine containing the active ingredient papaverine hydrochloride.

The action of the drug is aimed at the smooth muscles of internal organs.

This means you won’t have to suffer from muscle weakness due to taking the drug, because Its action does not affect the striated muscles.

As a concomitant, when taking papaverine, a mild sedative effect occurs.

Papaverine is produced in the form of tablets, injection ampoules and rectal suppositories.

The most convenient to use, of course, are tablets. They can be taken anytime, anywhere. Injections are made in a special way, without speeding up the rate of entry of the drug into the blood, therefore, for this procedure it is better to visit a special room.

However, pregnant women are more often prescribed papaverine in suppositories to ensure a milder effect on the body and not harm the baby.

Moreover, the price of candles is quite reasonable and ranges from 85 rubles. for a blister of 10 pieces. Why are suppositories with papaverine prescribed to pregnant women?

Doctors' opinions on the use of papaverine

According to experts, papaverine in the form of a drug for rectal use is safe for the health of the expectant mother and child. However, self-medication and dose adjustments should not be allowed without the advice of a specialist. Exceeding the prescribed dosage can lead to a deterioration in the woman’s well-being, including the need for hospitalization.

Dose adjustments should only be made by the attending physician if the clinical situation changes.

Papaverine does not have any negative effects directly on the fetus. This drug is approved for use at any stage of pregnancy if there are indications and no contraindications. While carrying a child, prescribing any kind of medication always raises many questions and concerns for the expectant mother.

A detailed study of the instructions for the drug, consultation with a doctor, and familiarization with relevant literature will help get rid of anxiety.

Suppositories with papaverine hydrochloride are safe for the child’s body and cannot harm him. You should accept the fact that compliance with the dosages recommended by the specialist minimizes the likelihood of adverse reactions from the mother’s body.

Therefore, the most important thing is to regularly consult with doctors and take any therapeutic measures only when prescribed by a gynecologist or other medical specialist.

During pregnancy, a woman tries to protect herself from various kinds of negative influences and factors that can lead to complications. And this includes not only all kinds of diseases, but also disorders, experiences, as well as stressful situations that pose a threat to the normal development of the baby and the maintenance of pregnancy. Unfortunately, it is not always possible to isolate yourself from stress, and sometimes situations arise that require medical attention. Nervous tension and stress also cause anxiety in the baby, which is why he becomes mobile. Its movements cause the uterus to tense, increasing its tone, which can cause contractions and threaten the continuation of the pregnancy. In this case, in order to prevent negative consequences, the doctor may prescribe special medications, one of which is suppositories with papaverine during pregnancy.

The use of suppositories with papaverine depending on the stage of pregnancy

As a rule, candles with papaverine or nosh-pa are not used separately.

Depending on the problem, antispasmodic drugs are usually prescribed in combination therapy with other drugs.

First trimester

In the first trimester of pregnancy, until the placental protection of the fetus has formed, the list of medications that have no contraindications for use is very limited. This is related to the popularity of prescribing papaverine suppositories as antispasmodics.

As a rule, at this time a woman suffers from toxicosis, so taking antispasmodic tablets is not advisable.

Most often, pregnant women are prescribed papaverine suppositories for increased uterine tone and a possible threat of miscarriage.

So, unlike tablets, suppositories have a more prolonged effect, since they are absorbed more slowly. This means that a woman can experience the positive effect of candles throughout the day.

The combined use of papaverine suppositories and no-shpa tablets in the treatment of uterine tone is possible; the decision on this tactic is made by the doctor.

Often, before the 16th week, the cause of uterine tone is insufficient production of the “pregnancy hormone” - progesterone. Therefore, papaverine and other approved antispasmodics are prescribed in conjunction with hormone therapy.

Second trimester

In the second trimester, the list of approved medications expands significantly.

Therefore, if there is a threat to the course of pregnancy, the health of the expectant mother and the fetus, more serious drugs that inhibit the contractile activity of the uterus may be prescribed:

Suppositories with papaverine are used by pregnant women as a means of immediate response to abdominal pain, increased blood pressure, etc.

This measure allows you to maintain the mother’s condition until she consults a doctor, who will determine the need and duration of further use of papaverine as an antispasmodic.

Can pregnant women use papaverine for constipation?

With prolonged and frequently recurring constipation, people suffering from this problem try to find the most effective remedy to help empty their bowels.

And it is not uncommon to find information that papaverine for constipation acts quickly and can be used as a first aid drug. The medicine has been used in medicine for more than 100 years, and during this period all the positive and negative properties of this medicine have been well studied.

Papaverine belongs to the group of opium alkaloids; the main effect of the drug is antispasmodic and hypotensive. The drug effectively eliminates spasms of smooth muscles located in the walls of internal organs. The instructions indicate that the medicine can be used as an antispasmodic to relieve symptoms:

Cholecystitis.
Renal colic.
Pylorospasm.
Spastic colitis.

The drug in the form of tablets and injections is used in the treatment of endarteritis, as an adjuvant for bronchospasm and angina.

Since the medication relieves tone from smooth muscles, it means that the walls of the digestive organs relax under its influence. That is, papaverine for constipation helps remove accumulated feces by eliminating spasm from the lower parts of the large intestine.

The laxative effect of papaverine is an additional property of the medicine, so it is rarely prescribed by doctors for constipation. This is especially true for tablet and injection forms of the product.

Papaverine for constipation is mainly used only in the form of rectal suppositories, which in official medicine are prescribed as a remedy for the treatment of hemorrhoids.

Papaverine suppositories, after entering the rectum, begin to dissolve and their active ingredients quickly penetrate the walls and general bloodstream, relieving spasms and facilitating bowel movements.

The opium alkaloid relieves pain well, so for constipation this medicine is recommended specifically if the pathology is accompanied by noticeable discomfort.

Suppositories with papaverine for constipation help if the lack of stool is associated with increased intestinal spasm. They should not be used for a long time, as this can lead to the opposite effect, that is, to an increase in the duration of constipation.

When using papaverine rectal suppositories to facilitate bowel movements, the following instructions should be followed:

After hygiene procedures, lie on your left side and insert a candle.
The suppository should be inserted to a depth of 2-2.5 cm.
After administration, you need to lie down for at least 20 minutes.

Papaverine in the form of rectal suppositories is not used for constipation more than three times a day. Increasing the frequency of administration leads to increased side effects and overdose.

When using papaverine, you should take into account all contraindications to this medicine, which also apply to rectal suppositories. You should refuse any dosage form of the drug if:

Glaucoma.
Severe liver failure.
Hypersensitivity of a person to the active ingredients of the drug.
AV block.

It is not advisable to use suppositories with papaverine for constipation if your blood pressure is too low. The hypotensive effect of suppositories during hypotension can cause severe weakness and dizziness.

The drug is contraindicated in children under six months of age. It is not recommended to use suppositories with papaverine as a remedy for constipation in older children.

There are much safer suppositories, for example, based on glycerin or sea buckthorn, which will not cause any harm to the child’s body and will help to quickly remove accumulated feces from the intestines.

Papaverine is often prescribed to pregnant women as a drug that relieves tone from the uterus. That is, this medicine is prescribed when there is a threat of miscarriage. In the hospital, the drug is most often given by injection, and suppositories with papaverine are prescribed for use at home.

The components of rectal suppositories are easily absorbed by the walls of the rectum, enter the bloodstream and begin their relaxing effect. Suppositories begin to act faster compared to the tablet form of the medicine.

Pregnant women who often experience constipation and aggravated hemorrhoids should not give up this drug. In case of simultaneous increase in uterine tone and prolonged absence of stool, papaverine will relieve two problems at once.

Papaverine is not contraindicated in any trimester of pregnancy; the drug effectively relieves pain that occurs with hemorrhoids and prolonged constipation. During pregnancy, it is better to put the suppository at night.

Although suppositories with papaverine for constipation are considered a safe drug, you should not use them constantly without a doctor’s prescription. Normalization of intestinal function should be carried out in accordance with the cause of the pathology, and this applies primarily to pregnant women.

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During pregnancy, a woman often faces a dilemma: whether to take medications, even those recommended by a doctor, or whether to refrain from “chemistry.”

However, pregnancy lasts more than one day or even a month. For nine long months, drug therapy may be required, for example, in order to maintain this very pregnancy and so that the baby in the womb feels comfortable until the due date.

Therefore, if a medical prescription includes taking medications, then this should be taken with due attention. Taking such drugs, as a rule, is justified, and their safety has been confirmed by generations of our mothers and grandmothers.

Among the medications prescribed to women during pregnancy, papaverine is often found.

Papaverine is the name of a medicine containing the active ingredient papaverine hydrochloride.

The action of the drug is aimed at the smooth muscles of internal organs.

This means you won’t have to suffer from muscle weakness due to taking the drug, because Its action does not affect the striated muscles.

As a concomitant, when taking papaverine, a mild sedative effect occurs.

Papaverine is produced in the form of tablets, injection ampoules and rectal suppositories.

However, pregnant women are more often prescribed papaverine in suppositories to ensure a milder effect on the body and not harm the baby.

Moreover, the price of candles is quite reasonable and ranges from 85 rubles. for a blister of 10 pieces. Why are suppositories with papaverine prescribed to pregnant women?

There has been no official scientific research on the effects of papaverine on the body of a pregnant woman, the course of pregnancy and fetal development.

Therefore, in the instructions, the manufacturers of the drug do not take responsibility for unequivocally recommending or prohibiting the use of the drug during pregnancy or lactation.

Indications for the use of papaverine during pregnancy may include:

This is the most common reason for prescribing papaverine both as a monotherapy and as part of complex therapy. Papaverine suppositories for uterine tone are prescribed to relieve strong tone of internal organs, including the uterus, and improve uterine blood flow.

High blood pressure.

The antispasmodic effect of the drug, affecting the walls of blood vessels, helps lower blood pressure.

Pain, colic caused by spasms of internal organs (as part of complex therapy).
Other situations requiring the use of antispasmodics and/or vasodilators on the body.

Most often, doctors recommend that pregnant patients have rectal suppositories with papaverine in their medicine cabinet, since a woman can install them herself to relieve sudden unpleasant symptoms.
The effect of the drug administered rectally manifests itself very quickly, within a few minutes.

How to use suppositories with papaverine during pregnancy? As a rule, suppositories are prescribed in a course three times a day at regular intervals.

Papaverine suppositories should be inserted into the anus while lying on your side.

It is advisable to do this after defecation so that there is no urge to have a bowel movement.

The instructions for the use of suppositories with papaverine say that their use is contraindicated if the patient’s medical history contains records of:

heart rhythm disorder caused by impaired AV conduction;
increased intraocular pressure (glaucoma);
liver, kidney failure, adrenal dysfunction (with caution);
violation of bronchial obstruction;
inflammation of the rectum.

More serious consequences may occur due to exceeding the prescribed dose: severe sedation, cardiac dysfunction, difficulty urinating and defecating, hypotension, dizziness, etc.

As a rule, candles with papaverine or nosh-pa are not used separately.

Depending on the problem, antispasmodic drugs are usually prescribed in combination therapy with other drugs.

As a rule, at this time a woman suffers from toxicosis, so taking antispasmodic tablets is not advisable.

Most often, pregnant women are prescribed papaverine suppositories for increased uterine tone and a possible threat of miscarriage.

So, unlike tablets, suppositories have a more prolonged effect, since they are absorbed more slowly. This means that a woman can experience the positive effect of candles throughout the day.

The combined use of papaverine suppositories and no-shpa tablets in the treatment of uterine tone is possible; the decision on this tactic is made by the doctor.

In the second trimester, the list of approved medications expands significantly.

Therefore, if there is a threat to the course of pregnancy, the health of the expectant mother and the fetus, more serious drugs that inhibit the contractile activity of the uterus may be prescribed:

ginipral;
bricanyl;
verapamil;
nifedipine;
injections and systems with magnesium.

Suppositories with papaverine are used by pregnant women as a means of immediate response to abdominal pain, increased blood pressure, etc.

This measure allows you to maintain the mother’s condition until she consults a doctor, who will determine the need and duration of further use of papaverine as an antispasmodic.

In the third trimester of pregnancy, there may be several reasons for prescribing suppositories with papaverine.

If the expected date of birth is still far away, then excess tension of the uterus becomes an indication for the introduction of suppositories with papaverine in late pregnancy.

When expecting delivery soon, suppositories with papaverine can be recommended as an indicator of “false” contractions.

If after their introduction the contractile activity of the uterus has stopped, it means that the due date has not yet arrived.

Suppositories with papaverine can be prescribed after the 38th week of pregnancy to soften the cervix.
Antispasmodic suppositories are also prescribed at the beginning of labor to reduce pain during the first contractions.

It has now become fashionable to argue that pregnancy and childbirth are natural conditions for any woman, during which it is extremely undesirable to interfere.

However, many modern mothers forget that maintaining sleep and rest schedules, eating well, giving up bad habits, and avoiding excessive stress is also a natural behavior that a woman whose destiny is motherhood should strive for.

In such conditions, common sense dictates during a critical period not to rely on chance, but to strictly follow all the instructions of a competent doctor in order to go through the entire nine-month pregnancy without loss, “laying a straw in advance” where there is a risk of “falling”.

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Almost every pregnant woman is familiar with the term “hypertonicity of the uterus.” Although this phenomenon is quite common, it is not a normal option and poses a danger to the course of pregnancy, including its premature termination. Fortunately, modern medicine has a large arsenal of drugs that can effectively relieve tension in the uterine muscles. Among them are the long-known and widely used Papaverine suppositories. Like any medicine, this drug can be used by a pregnant woman only as prescribed by a doctor, however, it is useful for every expectant mother to know all the nuances of its effect on the body and the basic rules of use.

Papaverine rectal suppositories are the most popular doctor’s prescription for uterine hypertonicity

Although Papaverine hydrochloride is actively prescribed by gynecologists to pregnant women for both outpatient and inpatient treatment, the instructions for the drug interpret its use during gestation (bearing a child) ambiguously. According to the recommendations provided by the manufacturer, the safety of using Papaverine by expectant mothers has not been established. Of course, this circumstance, combined with a doctor’s prescription that has already been received, will confuse a woman who is conscious about the use of medications during pregnancy.

It should be noted that clinical studies of the effectiveness and safety of the use of the drug Papaverine in pregnant women have not really been conducted. Nevertheless, the long-term practice of using Papaverine clearly demonstrates its positive effect on the course of pregnancy and, at the same time, complete safety for the fetus.

Papaverine suppositories are prescribed at any stage of pregnancy if a woman has or is suspected of having the following conditions:

Uterine hypertonicity is the most common diagnosis made during pregnancy. Hypertonicity is tension in the myometrium (the muscular layer of the uterus), which can occur for a number of reasons (stress, excessive physical activity, hormonal reasons, etc.) and can lead to premature termination of pregnancy.
Arterial hypertension - a persistent increase in blood pressure - is a fairly common phenomenon in late pregnancy.
Colic (liver, kidney, intestinal, etc.) is sudden, cramping pain caused by muscle spasm.
Bronchospasm is a pathological narrowing of the bronchi.
Severe increase in body temperature (in such cases, Papaverine is used as part of a lytic mixture).

Papaverine can also have a positive effect on constipation if it is caused by muscle spasms (spastic constipation). For atonic constipation, which is caused by a decrease in intestinal muscle tone, Papaverine will only worsen the situation.

The drug Papaverine is produced in several pharmaceutical forms:

solution for injections;
rectal suppositories;
pills.

During pregnancy, Papaverine is most often prescribed in the form of suppositories. This form has a number of advantages:

convenience and versatility of independent use by a woman;
complete and rapid absorption of the drug through the rectum;
increased therapeutic effect due to the proximity of the uterus.

Each Papaverine rectal suppository contains 20 mg of active ingredient.

The active substance of this product is papaverine hydrochloride, a myotropic antispasmodic. In this regard, the drug acts in two directions:

Relieving tension in the smooth muscles of internal organs (the product affects not only the uterus, but also the organs of other systems - urinary, digestive, respiratory).
Vasodilation and increased blood flow, due to which the drug is able to reduce blood pressure (hypotensive effect).

With regular use of Papaverine, women note its calming effect - the level of anxiety is significantly reduced, the heart rate is stabilized, which has the most positive effect on the course of pregnancy.

The mechanism of action of the drug in the form of rectal suppositories is as follows:

The suppository, after being placed in the rectum, melts under the influence of body temperature.
The active substance is instantly absorbed into the blood.
In blood plasma, papaverine binds to proteins.
The bloodstream carries papaverine to all systems and organs of a woman, including the muscle tissue of the uterus.
The active substance of the drug has a relaxing effect on smooth muscles.
Papaverine is excreted from the body by the kidneys in the form of metabolites (metabolic intermediate products).

The treatment regimen with Papaverine during pregnancy is prescribed only by a doctor in accordance with the individual characteristics of the woman’s body and the diagnosis. As a rule, the duration of taking the drug is 2–3 weeks, the daily dose is 2–4 suppositories. The doses of the drug are distributed evenly throughout the day.

It is important to remember that Papaverine suppositories are produced only for rectal use - they should under no circumstances be used vaginally.

The rules for administering rectal suppositories are as follows:

Before inserting the suppository, you must wash your hands thoroughly.
Since candles melt very quickly upon contact with your hands, before opening the blister, you can hold the unopened candle in the refrigerator or under running cold water for some time.
It is convenient to use disposable gloves or finger caps to administer the suppository.
It is better to administer the drug while lying on your side.
The candle must be placed behind the muscle sphincter, pushing it 2.5–5 cm deep.
After administering the product, it is better to lie on your side for a few more minutes to avoid leakage.
After completing the procedure, you should wash your hands thoroughly.

It is most convenient to insert rectal suppositories in a lying position

As a rule, suppositories with Papaverine are easily tolerated by pregnant women, however, in isolated cases (with prolonged and uncontrolled use), the following side effects may occur:

redness and itching of the skin (allergic reaction);
drowsiness;
dizziness;
heart rhythm disturbances;
increased sweating;
decreased blood pressure;
constipation;
nausea.

Rectal suppositories with Papaverine are contraindicated in the presence of the following conditions and diseases:

individual intolerance to the components of the drug;
glaucoma;
liver or kidney failure;
heart rhythm disturbances;
AV block (atrioventricular block).

Papaverine should be used with caution in cases of adrenal dysfunction, hypothyroidism and arterial hypotension (low blood pressure).

The only complete analogues of rectal suppositories with Papaverine are preparations of other pharmaceutical forms of release - tablets and solution for injection. If we talk about drugs with similar effects, then in modern gynecology such drugs as No-shpa, Magne B6, Utrozhestan are used. Their effect is based on the antispasmodic properties of other active ingredients.

Drug name	Active substance	Medicinal effects	Release form	Indications	Contraindications
Papaverine Hydrochloride (tablets)	Papaverine hydrochloride	Antispasmodic; hypotensive.	Pills	Smooth muscle spasm: abdominal organs; peripheral vessels; cerebral vessels; hearts; bronchospasm.	Hypersensitivity; AV block; glaucoma; severe liver failure.
No-shpa (Drotaverine)	Drotaverine hydrochloride	Antispasmodic	Pills	Spasms of the smooth muscles of the abdominal organs; tension headache.	Hypersensitivity; severe renal or liver failure; severe heart failure; hereditary galactose intolerance, lactase deficiency and glucose-galactose malabsorption syndrome.
Magne B6 (Magnefar, Magnelis)	Magnesium citrate; pyridoxine hydrochloride.	Replenishes magnesium deficiency. Magnesium, in turn, is involved in many body processes, including the transmission of nerve impulses and muscle contraction.	Pills	Muscle pain and spasms; cardiopalmus; increased fatigue.	Hypersensitivity; renal failure; phenylketonuria; hereditary galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency.
Utrozhestan	Progesterone (natural micronized)	Gestagenic – replenishment of the deficiency of female sex hormones.	Capsules for oral and vaginal administration.	Hormone replacement therapy; prevention of premature birth in women at risk (with shortening of the cervix or a history of premature birth); threatened abortion or prevention of habitual abortion due to progesterone deficiency.	Hypersensitivity; severe liver diseases; deep vein thrombosis, thrombophlebitis, thromboembolic disorders; porphyria.

During the first trimester of pregnancy, I was diagnosed with “Threatened miscarriage.” A huge number of medications were prescribed. One of them was Papaverine Hydrochloride suppositories. I took them every day at night, and in the first days even in the morning and at lunchtime. The doctor said that I simply had to put a candle on at night, and in the morning and at lunch - depending on how I felt. Although, it’s strange, what if I differentiate my condition incorrectly? The action of papaverine begins almost five minutes after administration. This is because it is so fast because there are a huge number of blood vessels in the rectum. And the medicine is absorbed directly into the blood, bypassing the gastrointestinal tract. In which, by the way, the medicine may linger and begin to act later if, for example, you have just eaten. The instructions say that there may be constipation. Did not have. Maybe a decrease in blood pressure. Blood pressure almost always decreased. Sometimes it was so strong that I had to lie down for several hours after taking the suppositories. I think it’s a plus that suppositories with papaverine help in complex treatment to remove the diagnosis of “threat”. I recommend it if prescribed by a doctor.

https://otzovik.com/review_1357179.html

Papaverine suppositories were prescribed during the first pregnancy. The first time I was prescribed these suppositories was when I was five months old, because my uterus very often began to tone up. I am very grateful to these candles, thanks to them I almost reached my due date (labor began a week earlier). I put one candle a day from five months to nine, when my stomach ached and was very hard, I put two candles a day - in the morning and in the evening. Some girls refused them because they felt good. I did not neglect the doctor’s prescriptions, because from six months there was a threat of premature birth.

https://otzovik.com/review_779662.html

Girls, I was in the hospital with a tone - they prescribed Papaverine suppositories. I used it - a white and blue box. They are difficult to open, even very difficult, but I was satisfied with the quality - no problems with insertion. When I left the hospital, I needed to continue the course, so I went to the pharmacy and bought it, but it turned out to be a different company - Biosintez. I didn't attach any importance to this. But at home... okay, they are also difficult to open, this has become habitual, but the composition itself, or how to put it correctly - everything crumbled in my palm when I opened it! I couldn't enter THIS. I started opening a new candle - the same mess - only half remained intact! Just some kind of nightmare. When this pack ran out, the new one turned out to be the same - there was no other one in the pharmacy. My God, they also crumbled into rubbish! I will never buy again!

MargaritkaNN

https://irecommend.ru/content/polnaya-byaka-0

I was going through my medicine cabinet and found the drug Papaverine, and immediately remembered how often I used these suppositories during pregnancy to relieve tone. I bought this drug in packs, since I often had uterine tone, and I was even in conservancy a couple of times because of this. I was given drops and injections of various drugs to relieve tone, and in combination with these drugs, my doctor constantly prescribed me Papaverine suppositories twice a day.

And even when I myself felt a slight tone and called my doctor, the first thing she told me was to use this drug. As much as I used this drug, I never noticed any side effects. Conclusion: Is Papaverine a good and proven drug? It really helps, especially in complex therapy. With severe tone, this drug alone will most likely not be enough. I say this based on my experience. I gave it four stars only because this drug is not such a strong antispasmodic that you can completely rely on it, but it does have a positive effect.

Therefore, I, of course, recommend this drug, but in any case, you should consult a doctor before using it.

Arishka the stomper

https://irecommend.ru/content/khoroshee-sredstvo-no-ne-panatseya-1

I was also prescribed Papaverine suppositories during pregnancy. The instructions for use then also confused me, but I consulted with a doctor, she reassured me. But there was a but... They didn't really remove the tone. Papaverine hydrochloride is a substance that weakens the contraction of a special type of muscle fiber - smooth muscle, they are found in the walls of internal organs. Its action does not affect skeletal muscles (that is, a person does not feel weakness), but relieves uterine spasms, reducing the calcium content in muscle cells, which is necessary for their contraction. Papaverine relaxes not only the smooth muscles of the uterus, but also the walls of blood vessels, and therefore can lower blood pressure. I had no side effects. The instructions for use warn of safety, but experts have long been convinced that candles do not carry anything bad.

https://www.babyblog.ru/community/post/living/459323

Suppositories with papaverine are a remedy that has been proven by many years of practice in maintaining pregnancy. Despite the large number of positive properties, Papaverine can provoke unpleasant and sometimes harmful side effects. Awareness of the specific effects of a drug on the body (for example, its ability to lower blood pressure) plays a very important role in determining the dosage and duration of treatment. That is why only a doctor can prescribe this drug based on the available indications and the individual picture of the course of pregnancy.

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The drug belongs to myotropic antispasmodics. Available in the form of suppositories, tablets and ampoules with solution. Its main purpose is to relax smooth muscles and blood vessels. It relieves spasms without affecting the central nervous system. Has a slight sedative effect. Relieves pain in smooth muscles, including the genitourinary system and gastrointestinal tract. Recommended for:

hypertonicity of the uterus;
spasms of cerebral vessels;
angina pectoris;
cholecystitis;
spastic colitis;
bronchospasms;
other.

Mostly doctors prescribe suppositories with papaverine during early pregnancy. The form, which is not the most convenient to take, will help the expectant mother alleviate her condition faster and more effectively than, for example, pills. With uterine tone, it is especially important, since the effect will be achieved in a matter of minutes.

Young mothers are sometimes confused about where to insert papaverine during pregnancy, and the phrase “rectal suppositories” causes slight confusion. It's simple: the drug is injected into the anus (in the butt, in simple terms). It is advisable that the woman does not have sharp nails, otherwise there is a risk of injury. To avoid getting confused about how to insert candles correctly, here’s a little instruction:

Before the procedure, wash your hands in warm water. Just not when it’s hot, because the candles melt quickly, which will make it difficult to enter. It is also recommended to first keep the drug in the refrigerator. By the way, it also needs to be stored in a cool place.
Open the package by carefully pulling the halves in different directions.
If you need to use only half the dose, then cut the candle in half along the longitudinal seam.
To maintain hygiene, it is recommended to use disposable gloves from the pharmacy.
Take the candle by the edge, point up. To make it easier to insert, moisten the edge with water or drop a little lubricant without Vaseline.
Take a comfortable horizontal position with one leg straight out and the other bent at the knee.
With one hand, open the anus slightly, moving the buttock to the side (lift it up).
Insert the suppository into the rectum, pushing it with your finger to a depth of 2.5-5 cm. Then squeeze the buttocks tightly for a few seconds.
Lie down for 5 minutes so that the papaverine does not jump out.
Wash your hands and throw away used material.

How to insert rectal suppositories correctly
If you still have questions about how to insert papaverine during pregnancy, consult your doctor.

In the early stages of pregnancy, the risk of spontaneous abortion or miscarriage is quite high. A young mother should lead not only a healthy, but also a calm lifestyle. But realistically speaking, only a few succeed. Work, nerves, an overly active life, sometimes fear and problems with the future dad provoke increased uterine tone. It is in this case that the drug “Papaverine” is prescribed, injections of which during pregnancy help relieve unpleasant symptoms and preserve the fetus. They can be administered both intramuscularly and intravenously.

As for tablets, they are prescribed extremely rarely. The thing is that it takes much longer to dissolve in the body and achieve an effect than with candles or injections.

Depending on the reason for prescribing the drug, only the doctor will be able to choose the most convenient dosage form and dosage schedule. For example, for blood pressure papaverine during pregnancy, the use of which is possible only under conditions of high levels, can be prescribed in the form of intravenous injections. If it is necessary to relieve vascular spasm, the doctor can make the following schedule: two to three suppositories per day at equal intervals.

In this case, in each individual case, possible side effects will be taken into account. You don’t need to prescribe the drug yourself! Only an observing doctor knows exactly how much papaverine is allowed during pregnancy!

Even though expectant mothers are often prescribed papaverine during pregnancy, the instructions for its use do not provide 100% confidence in the safety of use. However, many years of observational experience shows that if the recommendations are followed and possible contraindications are taken into account, it is very well tolerated. In the shortest possible time, the mother feels relief, her heart rate becomes even, she calms down, which certainly has a beneficial effect on the child.

Like any medicine, regardless of the form of release, the drug “Papaverine” can also have a negative effect on the body of the expectant mother. Possible side effects include:

allergies,
pressure reduction,
constipation,
drowsiness,
nausea,
dizziness,
increased sweating;
heart rhythm disturbance.

Heart failure occurs most often due to rapid intravenous or intramuscular administration. But the remaining effects can be obtained by the mother who independently increases the recommended dose.

Those for whom doctors will definitely not prescribe the drug, but will select an analogue, include pregnant women with the following disorders in the functioning of the body:

liver diseases;
with problems in the thyroid gland;
with tachycardia;
with abnormal bowel movements (frequent constipation);
with increased intraocular pressure;
with low blood pressure.

If the doctor has prescribed you to take the drug “Papaverine” during pregnancy, then there is no need to worry about the condition of the child. It does not have any negative effects on the fetus! But you cannot prescribe it yourself, even if you suspect or have a confirmed diagnosis of uterine tone. The fact is that in some cases it will not be effective enough. In a hospital setting, the pregnant woman will be prescribed an additional set of medications. If she is treated on her own, then the chance of losing the child greatly increases.

It controls the tone of the uterus, calms the nerves and muscles (fallopian tubes, uterus, stomach).

with endometriosis, mucus appears randomly, but if the tone of the uterus does not increase, there is no harm to the embryo

Uterine tone in the early stages of pregnancy is a very common phenomenon that at least half of mothers experience.

These substances do not affect the tone of the uterus and do not pose a danger to the woman.

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