Indications and instructions for use of the drug Macmiror during pregnancy


Compound

Vaginal cream contains:

  • nystatin , nifuratel ;
  • glycerin , sodium methyl parahydroxybenzoate, propylene glycol, triethanolamine 30%, xalifin, sodium propyl parahydroxybenzoate, 70% sorbitol solution, water.

Vaginal suppositories include:

  • nystatin, nifuratel;
  • glycerin, titanium dioxide, sodium ethyl parahydroxybenzoate, gelatin, yellow iron oxide.

Pharmacodynamics and pharmacokinetics

Macmiror Complex is a combined local antifungal drug. Nifuratel effectively fights many types of bacteria, fungi and protozoan microorganisms (for example, Trichomonas vaginalis ).

Nystatin is an antifungal antibiotic. It disrupts the permeability of the fungal membrane, after which the cell is destroyed. Particularly effective against Candida albicans .

The combination of nystatin and nifuratel makes it possible to increase the effectiveness of the antifungal action and expand the range of indications for use.

McMikor Complex has low toxicity, due to which it does not destroy the physiological flora, does not cause dysbacteriosis and quickly restores vaginal normocenosis.

Pharmacological properties of the drug

Hormonal changes during pregnancy lead to a decrease in immunity, so viruses and bacteria begin to attack the woman’s body with redoubled force, causing, first of all, changes in the microflora. This leads to the development of inflammatory processes in the genital organs. To eliminate negative consequences, Macmiror is often prescribed during pregnancy, reviews of which are mostly positive. This is an antibacterial drug that has a gentle effect on the vaginal microflora and does not cause the development of dysbacteriosis.

One of the main active ingredients of the drug is nifuratel, which is effective against various bacterial pathogens. This substance itself is not particularly safe and has some side effects. Thanks to recent pharmacological developments, it has been possible to minimize these negative effects, resulting in the appearance of this drug, which can also be used during pregnancy.

Hormonal changes during pregnancy lead to a decrease in immunity, so viruses and bacteria begin to attack the woman’s body with redoubled force, causing, first of all, changes in the microflora. This leads to the development of inflammatory processes in the genital organs. To eliminate negative consequences, Macmiror is often prescribed during pregnancy, reviews of which are mostly positive. This is an antibacterial drug that has a gentle effect on the vaginal microflora and does not cause the development of dysbacteriosis.

One of the main active ingredients of the drug is nifuratel, which is effective against various bacterial pathogens. This substance itself is not particularly safe and has some side effects. Thanks to recent pharmacological developments, it has been possible to minimize these negative effects, resulting in the appearance of this drug, which can also be used during pregnancy.

Its cost is quite high and it is not classified as a budget product or an affordable price category. If we talk about the cost of the latter, produced in tablet format, the price varies from 600 to 980 rubles, depending on the pharmacy outlet and the concentration of the active ingredient. If we talk about the cost of the cream, the price varies from 470-550 rubles.

Hormonal changes during pregnancy lead to a decrease in immunity, so viruses and bacteria begin to attack the woman’s body with redoubled force, causing, first of all, changes in the microflora. This leads to the development of inflammatory processes in the genital organs. To eliminate negative consequences, Macmiror is often prescribed during pregnancy, reviews of which are mostly positive. This is an antibacterial drug that has a gentle effect on the vaginal microflora and does not cause the development of dysbacteriosis.

One of the main active ingredients of the drug is nifuratel, which is effective against various bacterial pathogens. This substance itself is not particularly safe and has some side effects. Thanks to recent pharmacological developments, it has been possible to minimize these negative effects, resulting in the appearance of this drug, which can also be used during pregnancy.

3 years.

The drug contains two active ingredients - nystatin and nifuratel.

Nystatin is an antifungal drug that is active against Candida fungus.

Nifuratel is a broad-spectrum antibiotic that has pronounced antibacterial, antifungal and antiprotozoal effects.

The product is available in the form of suppositories, tablets (containing only an antibiotic) and vaginal cream.

Macmiror complex is indicated for the local treatment of vulvovaginitis that was caused by candidiasis, chlamydia or trichomonas.

Side effects occur rarely and manifest themselves in the form of local irritation and itching.

Macmiror Complex is an antimicrobial agent for topical use. The active components included in the drug have a pronounced antifungal, antiparasitic and antibacterial effect on the female pelvic organs.

Nifuratel, which is part of the suppository, is a derivative of Nitrofuran and exhibits high therapeutic activity against bacteria, fungi and Trichomonas.

Nystatin belongs to the polyene group of antibiotics. The drug acts directly on the pathogen cells, disrupting their permeability and causing their death. Nystatin exhibits high activity against yeast-like fungi of the genus Candida.

The combination of two active components of the drug Macmiror Complex allows you to achieve the most pronounced therapeutic effect in relation to pathogens of female genital infections.

Under the influence of Makmicor Complex suppositories, the physiological microflora of the vagina is not disturbed, which makes it possible to avoid dysbiosis of the genital tract and restore the natural pH environment of the vagina in the shortest possible time.

It is not recommended to perform vaginal douching while using the drug Macmiror Complex, since such procedures reduce the therapeutic effect of suppositories.

When using oral Nystatin tablets simultaneously, you should be careful with the dosage to avoid the development of systemic signs of overdose.

The simultaneous use of topical antifungal and antibacterial drugs - creams, vaginal tablets and gels - is not recommended, as this increases the risk of developing vaginal dysbiosis.

Suppositories can be purchased in pharmacies only with a prescription from a doctor. It is recommended to keep the medicine away from children, avoiding heating the package and exposing it to direct sunlight. The maximum storage temperature should not exceed 25 degrees. The shelf life of suppositories is indicated on the packaging and is 3 years from the date of manufacture.

Instructions for use of suppositories and cream Macmiror Complex (Method and dosage)

The drug is used intravaginally .

Every day for 8 days before bedtime, apply 2.5 g of cream using an applicator. The instructions for Macromir Complex suppositories are the same as for the ointment; 1 suppository should be administered per day. To maximize the effect, the suppository is inserted into the upper part of the vagina. After menstruation, treatment can be repeated if necessary.

In childhood, vaginal suppositories are not used; in such cases, it is recommended to use a cream with an applicator .

Why is giardiasis dangerous during pregnancy?

The presence of parasites in the body negatively affects its functioning, especially when it comes to the body of a pregnant woman. Hormonal changes reduce the ability of the immune system to resist various types of parasites. Giardia during pregnancy is an alarm bell, because giardiasis can negatively affect the intrauterine development of the fetus. During the disease, the level of red blood cells in the blood decreases, and as a result, the fetus suffers from a lack of oxygen. Protozoa parasitize the intestines and interfere with the normal absorption of nutrients. The fetus does not receive sufficient nutrition for normal development, which threatens intrauterine pathologies.

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giardiasis in pregnant women

Symptoms of giardiasis in pregnant women

Due to the tiny size of the parasite, the disease may be asymptomatic at first. When there is too much lamblia, intoxication of the body occurs. There are two forms of giardiasis - chronic and acute. In the acute form, the following symptoms are observed:

Lack of timely treatment threatens the disease to become chronic, the symptoms of which are:

Causes of giardiasis infection

Giardiasis during pregnancy occurs against a background of weakened immunity. The causative agents of the disease are protozoa from the class of flagellates. These microscopic living creatures enter the human body due to poor personal hygiene. Giardiasis can occur if you eat unwashed vegetables and fruits or drink unboiled water, even spring water. Flies are also the spreader of the disease. The disease can be transmitted sexually with insufficient hygiene. The risk of infection is also high in open water bodies or swimming pools. For this reason, pregnant women should avoid swimming there.

pregnant woman in the lake

How does giardiasis affect pregnancy?

In the body of a pregnant woman, Giardia not only affects her, but also causes serious harm to the fetus. Just look at oxygen starvation caused by a decrease in the level of red blood cells. Fetal hypoxia can lead to very serious consequences, including intrauterine pathologies. Increased body temperature at 4-14 weeks of pregnancy, a typical picture for the acute form of giardiasis, can cause the death of the embryo. At very high temperatures, blood clotting increases, which can lead to the formation of a blood clot in the placenta and inevitable death of the fetus. Prolonged diarrhea interferes with the normal absorption of nutrients and water.

Diagnosis of giardiasis

The peculiarity of this disease is that it is almost impossible to determine it by its symptoms. The only option for making a correct diagnosis is blood and stool tests. The blood is tested for the presence of specific antibodies in it, and the feces are examined using the PCR method. So far this is the most accurate analysis for giardiasis. It is carried out for 4 days, taking biomaterial every day. To obtain the most accurate result, you must follow the rules for preparing for analysis. Do not take rectal suppositories or laxatives 2-3 days before collecting biomaterial.

Blood test for toxocariasis

Stages of treatment of giardiasis in pregnant women

It is necessary to begin treatment for giardiasis immediately after its diagnosis. You should not self-medicate, because taking most medications is contraindicated during pregnancy. The specialist will be able to prescribe a course of complex therapy aimed at getting rid of parasites, as well as the consequences of their presence in the body.

Treatment of giardiasis can be divided into three stages:

Medicines and diet for giardiasis

Treatment is carried out primarily with antibiotics. Use:

Reception is prescribed in short courses from 3 to 5 days. Treatment should be carried out under the full supervision of a physician. If severe allergic reactions occur, antihistamines can be prescribed, but they should be taken with caution, as they can negatively affect the fetus. In case of serious digestive disorders, you should start taking Smecta or any other enterosorbent that protects the intestinal mucosa and prevents the absorption of toxins into the blood.

Smecta

Also, a pregnant woman must follow a special diet for giardiasis. Since a woman’s digestive system suffers the most, it is important to normalize intestinal function and suppress the vital activity of Giardia. The diet consists of consuming large amounts of fermented milk products, fresh vegetables and fruits, as well as foods containing high levels of plant fiber. It is necessary to exclude from the diet foods that contribute to the growth of parasites. These include foods containing “fast” carbohydrates, spicy and salty foods. You should eat fatty foods with caution.

There are some features of cooking and choosing food:

Prevention of giardiasis during pregnancy

Giardiasis is a dangerous disease for a pregnant woman, which means it is better to prevent the disease than to deal with its consequences. The main way to prevent giardiasis is to follow basic hygiene rules. Do not consume unboiled water, unwashed vegetables and fruits. It is better for a pregnant woman to avoid swimming in open water or public pools. It is also necessary to maintain cleanliness in your home. Not only the pregnant woman herself, but also her household should adhere to hygiene standards.

Another important factor for the prevention of giardiasis during pregnancy is maintaining the woman’s immune system. For these purposes, the doctor prescribes vitamin complexes for pregnant women.

Giardiasis is a disease that can and should be treated. During pregnancy, the disease has a good prognosis if treated correctly and in a timely manner. Only a specialist, using a series of tests, will be able to make a correct diagnosis and prescribe the correct treatment. You should not rely on traditional methods and self-medicate. During pregnancy, a woman is responsible not only for her body, but also for her child.

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Price for McMirror Complex

The cream in Russia costs 465 rubles, in Ukraine – 172 UAH.

The average price of McMirror Complex candles in Russia is 491 rubles, in Ukraine – 109 UAH.

  • Online pharmacies in RussiaRussia
  • Online pharmacies in UkraineUkraine

ZdravCity

  • Macmiror Complex cream vaginal.
    30gDoppel Pharmaceutical S.r.L. RUR 841 order
  • Macmiror Complex vaginal capsules. 200000IU + 500 mg 8 pcs. Doppel Pharmaceutical S.r.L.

    RUR 761 order

Pharmacy Dialogue

Europharm* 4% discount using promo code medside11

  • Macmiror complex vaginal capsules 200000IU plus 0.5g N8Doppel Farmacheutichi S.r.l.

    922 rub. order

show more

Pharmacy24

  • Macmiror Complex 30 g cream Doppel Pharmaceutical Srl, Italy
    378 UAH. order

Side effects

The official instructions for the drug do not indicate absolute contraindications to the use of the drug Macmiror during pregnancy. The only indication is hypersensitivity to individual components or insensitivity of pathogenic microflora to this drug.

After conducting research, the safety of this drug for a woman and her unborn child was proven. Some experts believe that long-term use of vaginal suppositories can cause premature labor or miscarriage. But this information has not been clinically confirmed, and most likely problems with childbirth are caused by the underlying disease, but not its treatment with the Macmiror complex.

Gynecologists often prescribe Macmiror suppositories to their patients, which already inspires confidence in them, so you should not be afraid to use the drug prescribed by your doctor if you are not intolerant to its individual components.

Headaches are a side effect of the medication

Possible side effects of the drug Macmiror complex.

  1. Allergic reaction, itching, skin rash, redness of the mucous membrane.
  2. General malaise, headaches.
  3. Dyspeptic disorders, nausea, diarrhea.

Negative effects may occur due to self-medication or non-compliance with the duration of treatment. As for overdose, such information was not received from patients, so at the moment this has not been recorded.

When using the drug, side effects may occur in the form of:

  • allergic reactions, itching, rash, redness of mucous membranes;
  • general deterioration of health, headaches;
  • disorders of the gastrointestinal tract, nausea, diarrhea.

Such negative consequences are often the result of self-medication and non-compliance with doctor’s recommendations. If pronounced side effects occur, you should consult a doctor to rule out a severe form of allergy. The doctor will also determine the advisability of further treatment with the drug. Negative manifestations disappear almost immediately after discontinuation of the medication.

Patients note another minor drawback of the drug. Brightly colored suppositories stain underwear. But this problem is not difficult to eliminate if you use panty liners during therapy. In addition, not everyone is happy with the considerable price of the product.

Vaginal suppositories are well tolerated by patients. Less than 10% of patients noted allergic reactions to the drug, which manifested themselves in the form of itching, redness, and rash.

Mild discomfort ceases to bother the woman after completing the course of treatment.

If the adverse reactions are severe, a doctor is consulted and a decision is made to replace the drug to avoid the development of a severe form of allergy.

The drug is generally well tolerated by patients. Persons with increased individual sensitivity to the components of the drug may develop the following adverse reactions:

  • Burning in the vagina;
  • Increased pathological discharge from the genital tract;
  • Itching in the vagina;
  • Foreign body sensation;
  • Redness of the mucous membranes of the genitals and rashes on the genitals of an allergic nature.
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