Duphaston during pregnancy

Action

To understand whether Duphaston can affect hCG, you first need to understand the concepts. This is very important, since many patients without medical education get confused about them. For example, some women think that Duphaston contains hCG, but this is not so.

Duphaston is a drug that contains artificial progesterone. It is prescribed to women who have a deficiency of this hormone in the body. Initially, it promotes conception, and after it occurs, it helps a woman bear fruit.

For example, with increased uterine tone, progesterone will have a relaxing effect on it and thereby allow the embryo to develop as harmoniously as possible. It also inhibits the growth of muscle fibers of the uterus and reduces the force of contractions of the organ. Duphaston has virtually no side effects and is therefore completely safe for a woman and her child.

To avoid various problems, the patient should always warn doctors that she is taking synthetic progesterone, since it may not be combined with other medications and may distort the results of some tests. For this reason, many women ask the question: “Does Duphaston affect hCG levels?”

As for hCG, it is a hormone that produces the chorion, a structure that ultimately transforms into the placenta. The production of hCG begins a few days after fertilization of the egg and continues throughout pregnancy. This hormone blocks the mechanisms that lead to menstruation and provokes increased production of estrogen and progesterone by the body.

Both Duphaston and hCG have a beneficial effect on the nervous system and reduce immunity (if a woman’s immunity works as usual, the body may perceive the fetus as a foreign organism and direct its forces to destroy it). All this together minimizes the risk of spontaneous abortion.

Composition of the drug "Duphaston"

The drug is a film-coated tablet containing 10 mg of the active substance dydrogesterone, which is an analogue of the real female hormone progesterone. The following substances are used as auxiliary components: lactose, starch, gelatin, magnesium stearate and talc. This composition of the drug is very effective; when used orally, it ensures the proper development of the endometrium and neutralizes the effect of male excess, which negatively affects the female body. When used correctly, the drug eliminates the deficiency of female sex hormones and thereby normalizes the functioning of the reproductive system of the female body, including reproductive function.

Relationship

The effect of Duphaston on hCG during pregnancy may be different. In most women, the level of human chorionic gonadotropin remains at the same level, but in some patients some changes still occur. This is because progesterone is partially controlled by hCG.

At the same time, Duphaston is a synthetic drug, which means that it only passively replenishes the deficiency of the necessary substance. The ovaries still continue to produce small amounts of progesterone. This leads to the fact that when taking Duphaston, hCG begins to increase.

That is why it is necessary to use Duphaston during pregnancy under the supervision of a qualified doctor. Despite the fact that hCG and progesterone are safe for the body, the specialist must still be careful. Under no circumstances should you engage in self-diagnosis or self-medication. Only doctors know exactly how Duphaston affects hCG and various processes in the body.

Despite the fact that Duphaston's effect on hCG can lead to an increase in the amount of the latter, in some cases its level still remains low. In such situations, experts suggest injecting gonadotropin, because its excess is much safer than its deficiency.

Duphaston and basal temperature

For those women who carefully approach the issue of conception, the question of the effect of duphaston on basal temperature is not surprising.
After all, you need to monitor your basal temperature so that you can calculate the day of ovulation. If a couple of days before the corpus luteum matures, the temperature increases, this signals that progesterone is being actively produced. Despite the fact that duphaston is an artificial analogue of a natural human hormone, laboratory tests and studies have ruled out its ability to affect basal temperature.

For this reason, there is no need to stop taking or monitor ovulation. The main effect of duphaston is to promote the attachment of the fertilized egg to the endometrial wall, thereby increasing the chances of a successful pregnancy outcome. You can monitor the presence of ovulation by purchasing a test that is similar in principle to a pregnancy test.

This medicine does not require self-prescription; it is important to follow the dosage recommended by your doctor and take the drug under his constant supervision.

Reliable signs of pregnancy before delay

Change in basal temperature

If a woman is attentive to her health, listens to all hormonal and temperature changes, then it will be easy for her to determine fluctuations in basal temperature. The idea is that when a woman ovulates, her body temperature rises to thirty-seven degrees. And it remains like this until the start of menstruation, and seven days before the menstruation itself it sharply decreases. So, if there are only a couple of days before menstruation, and the basal temperature is still high, then there is every chance that she is pregnant.

One of the early symptoms, and extremely reliable, is an increase in the hCG hormone. Thanks to it, the placenta is formed, in which the fetus subsequently develops. And when a large amount of hCG is detected in a woman’s blood, then this is most likely a sign of the woman’s pregnancy. And to determine it, you must either take a pregnancy test. But it is worth considering that hCG can give fairly accurate results only on the tenth day of pregnancy, not earlier.

Side effects of duphaston

Know that in the CIS, gynecologists prescribe duphaston during pregnancy as if it were a vitamin. Well, it makes the doctor feel better. Well, this is the fashion, but gynecologists prescribe it, and it’s good...

Yes, it may be good for the doctor and the mother, but it is completely unknown how this will affect the reproductive system and the general health of the unborn child. Yes, you will maintain the pregnancy on progesterone, but then you will have to raise the child. And besides, if in early childhood the occurrence of allergies and asthma can be attributed to bad products with preservatives and all sorts of “E” or dirty air, then in adolescence, “progesterone” girls often develop polycystic ovary syndrome, acne, metabolic disorders, and Boys filled with progesterone in utero have a change in sexual orientation.

The fact is that in the USA and Europe the use of synthetic progesterones (in particular, Turinal) is prohibited due to the fact that its use in the early stages of pregnancy (up to 4 months) can cause minor malformations of the fetus. Duphaston and Utrozhestan are practically the same Turinal, of course, safer because they are more modern, but nevertheless, many pediatricians are already sounding the alarm and even the term “progesterone children” has appeared. These are children, as a rule, with adrenal insufficiency - that is, potential allergies and asthmatics.

Hormonal changes

When the fetus matures and develops in a woman’s body, this is always confirmed by hormonal changes. It is precisely this hormonal transformation of the body that leads to the appearance of those same, barely noticeable signs of delay before pregnancy.

Progesterone or the “pregnancy hormone” begins to be actively produced in a woman’s body as soon as a woman becomes pregnant. The hormone helps supply all the necessary elements to the embryo. Although often, progesterone affects not only the uterus, but also other organs.

Progesterone, influencing the human nervous system, produces another hormone - human chorionic gonadotropin, and together they both contribute to the appearance of the first signs of pregnancy even before the menstrual cycle is delayed.

The effect of Duphaston on the body

Dydrogesterone is the substance that forms the basis of Duphaston.
The structure of dydrogesterone is similar in structure to a natural hormone, which performs the same functions in a woman’s body. But in its composition, Duphaston is not as active as its previous analogues, so it does not lead to serious consequences at all. Duphaston affects a woman’s body in almost the same way as progesterone. After all, as you know, this hormone plays a huge role in normal conception and gestation.

Additional signs of pregnancy before delay

Implantation bleeding

It is not uncommon for women to experience bleeding in the early stages of pregnancy. But you should not be alarmed, as this may be due to the fact that the fertilized egg is implanted into the wall of the uterus. Therefore, a woman is not able to feel any changes until this moment, because from the moment of fertilization of the egg until implantation, seven days pass when the egg does not come into contact with the woman’s body.

Frequent urge to urinate

And this symptom appears due to relaxation of the woman’s bladder sphincter.

Vaginal discharge

Heavy discharge is a normal condition of the cervix during pregnancy, when additional mucus protects the uterus from any external influences. This process is also called “mucus plug”.

Breast tenderness

A woman's breasts are gradually preparing for feeding. Therefore, her nipples are sensitive to any touch, they darken, and at a later date, colostrum can be detected.

Cramps in the lower abdomen.
Increased or decreased sexual desire.

Side effects

The most common side effects of Duphaston are:

peripheral edema of the arms and legs (due to the properties of Duphaston to change the composition of fluids in the body);
urticaria and skin itching (due to the effect of the drug on liver function);
headache and migraine;
increased sensitivity of the mammary glands.

Rarely observed:

breakthrough bleeding (in this case, the doctor may increase the single dose of the drug);
Quincke's edema;
hemolytic anemia.

In case of overdose, manifestations from the digestive system (nausea, vomiting) and the endocrine system (enlargement and soreness of the mammary glands) are aggravated. special antidote , so treatment is carried out symptomatically . You should also immediately seek help from a doctor .

Signs of early pregnancy before missed period

Toxicosis Often women complain of vomiting in the morning. And if this happens about two times a day, then this is considered normal during pregnancy, but if more, then you need to consult a doctor. This happens because the vomiting center is irritated by various very bright and rich odors, or by exacerbation of stomach problems. But nevertheless, this sign may not always mean pregnancy. Sometimes this is the cause of various gastrointestinal pathologies. And in this case, differential diagnosis is carried out.
Change in sense of smell A woman may begin to experience an aversion to previously loved smells and foods. We know that sometimes a pregnant woman has special cravings for a particular food. Sometimes it’s just sour and salty food. And all this madness is happening because of the same hormone, which has a special effect on the medulla oblongata.
Reduced blood pressure Progesterone has an antispasmodic effect, which is the main reason for the drop in blood pressure. Thus, the vascular muscles become extremely sensitive to this hormone; it is difficult for calcium to contact calmodulin and this leads to a lack of vascular contraction and relaxation. This is normal during pregnancy, because it is necessary for bearing a fetus. But if this process is absent, then you need to sound the alarm, because this can cause diseases such as gestosis and placental insufficiency.
Frequent urge It is frequent urination that is the first sign of pregnancy in the early stages. This happens because blood flow in the genitourinary organs increases, which accelerates the filtration of urine in the kidneys. The amount of urine increases, and entering the bladder, stretching it causes frequent urge. But it is also very important to know that such urges can be the cause of diabetes, so a sugar test is almost always prescribed.
Heavy discharge When progesterone affects the vaginal glands, it causes the discharge to become more abundant and white in color. But if you notice bloody discharge, you should immediately visit a doctor.

Duphaston during pregnancy

So, the desired pregnancy has arrived: the test showed two distinct lines, sentimental tears came, the happy or frightened future father was informed of the imminent emergence of a new status, and you are already looking in the mirror to see if your belly has become large and are touched by the advertising of diapers on TV.

The next item on a decent and responsible woman’s agenda is usually a visit to the gynecologist. After the ultrasound examination, everyone exhaled calmly: “Congratulations! Everything is in order, the pregnancy is uterine, there is a fetal heartbeat... Only you are somehow nervous! Have a drink, duphaston (morningstan)! It will not be worse!". At this point in the doctor’s appointments, the expectant mother needs to be very careful and wary. Perhaps you should ask the doctor a bold and immodest question: “Why?” What are the indications for taking duphaston? The doctor must give a reasoned reason why YOU should drink duphaston.

Duphaston is still a hormone.

Duphaston and utrozhestan, which are most often prescribed during pregnancy, are analogues of natural progesterone. However, duphaston is a synthetic progesterone, and utrozhestan is microionized natural progesterone.

Despite all their “naturalness,” they can cause side effects typical of any drug. These are drowsiness, lethargy, worsening mood, problems with liver function (therefore, the use of these drugs is prohibited in case of impaired liver function, especially in Gilbert, Rotor and Dabin-Johnson syndromes).

A gynecologist can make “scary eyes” and say that, in general, progesterone is useful for maintaining pregnancy. Yes, definitely. But we need a HEALTHY child, not one saved at any cost!

Early miscarriages in 80% of cases occur due to genetic mutations of the fetus. Let me explain: if the pregnancy does not continue and is terminated, then most likely you did not have a child with one or another pathology. A miscarriage before 3 months is a kind of natural selection!

Only in the CIS countries is it customary to maintain pregnancy at all costs! The woman is hospitalized and actively treated. The following are used: no-spa, magnesia, dicynon, magne B6 and so on. All these drugs do NOT help maintain a pregnancy if a miscarriage is destined. What will help maintain pregnancy most of all is calmness of the nervous system, which is very difficult to obtain in a hospital, even in the best one.

The very first symptoms of pregnancy before delay

Each woman’s body is individual and feels the approach of pregnancy in its own way, therefore, when a woman receives a positive pregnancy test, this only confirms her first symptoms of pregnancy. So what are the early signs of pregnancy before delay?

Bad feeling. This period is accompanied by periodic headaches, fever, and fatigue. This is due to the fact that the immune system really weakens, but you should not resort to antibiotic treatment. Traditional medicine is more suitable here.
Breast tenderness. After just a week, the breasts become sensitive and painful sensations appear when palpated. Although there are also cases when such unpleasant sensations do not occur, even during pregnancy.
Change in skin color around the nipples.
Increased BT. If you monitor your menstrual cycle and often measure your basal temperature, then you will easily notice a sharp change, actually an increase in temperature. So, progesterone increases the temperature, and another hormone, estrogen, usually lowers it, but when they suddenly meet, the so-called combination, a sharp jump in temperature occurs, which leads to an increase in BT.
Bloody issues. This phenomenon really takes place, because it is associated with the implantation of the fetus into the woman’s uterus, and this is a week after conception. But sometimes slight bleeding is possible in the presence of cervical erosion. Since blood circulation in the cervix increases, blood is released.
Restless sleep. In women, the first symptom of pregnancy can also be constant drowsiness, restless dreams, and constant anxiety, a feeling of weakness and fatigue, even with a normal sleep schedule.
Temperature changes. In the first, early stages of pregnancy, women's body temperature increases and blood pressure drops. This may be accompanied by the fact that they feel either hot or cold.
Excessive salivation. Due to irritation of the salivary center, expectant mothers may even lose up to two kilograms in weight.
Change in sense of smell. Also, one of the earliest symptoms of pregnancy is a change in preferences for smells and tastes. This occurs in the second week of pregnancy, and is due to disruption of the central nervous system.
Headache. Migraines and frequent headaches occur as a result of a spontaneous increase in hormones in the blood. And only at the end of the first trimester the pain subsides.
Bloating and constipation. Also, a common sign of pregnancy in the early stages of pregnancy is bloating and enlargement of the abdomen. The uterus has not yet enlarged enough to be noticeable, so the reason is different. The fact is that metabolic processes in the body slow down, food passes through the intestines much more slowly, which leads to bloating.
Frequent urination. Due to the increased amount of hormones in a woman’s body, blood circulation increases, blood flows significantly to the pelvic organs, the bladder stretches and the impression of urinary fullness is created. But the urge is usually painless.
Thrush. When a woman is pregnant, then the level of oxygen in vaginal secretions increases. In this way, the vagina is protected from all sorts of microorganisms getting into it. And such an environment is ideal for the development of yeast. Therefore, it is necessary to fight thrush so as not to infect the child.
Increased appetite. A woman wants to eat constantly, and her taste characteristics can change beyond recognition. She may fall in love with something that she had never recently consumed in her diet.
Lack of menstruation. This is the most common sign, although it does not always mean pregnancy. After all, all sorts of stress reactions of the body can cause the absence of menstruation.

Consequences of taking

Despite the fact that the drug is very similar in its molecular structure to progesterone, individual reactions of the body are possible. This is minimal discomfort, which allows you to do the most important thing - maintain the pregnancy.

increased sensitivity of the mammary glands;
uterine bleeding (dosage changes);
abdominal pain;
weakness, malaise;
headaches, migraine;
insomnia;
itching, rash, urticaria (very rare);
hemolytic anemia (isolated cases);
edema syndrome.

In addition, there are conditions in which the drug should not be taken.

diabetes;
diseases of the excretory system;
rare hereditary diseases;
disruptions in the functioning of the cardiovascular system;
individual intolerance.

Duphaston should not be taken with medications containing estrogen. All appointments are controlled only by a doctor.

If a pregnant woman makes a mistake with the dose and takes more than prescribed, gastric lavage is necessary. There are no special antidotes; only symptoms that arise are treated. In any case, if adverse reactions or overdose occur, you should seek medical help.

What is hCG?

In another way, this concept sounds like beta hCG or general hCG.
These are 3 different names for one element called human chorionic gonadotropin. The element in question is a full-fledged hormone, which is formed just during a woman’s pregnancy, when a certain restructuring of the hormonal system occurs, characteristic of all women expecting the birth of a child. This hormone is produced in large quantities as a result of the influence of the placenta.

The importance of this hormone is so great that the entire period of pregnancy in a woman there is a change in its amount in the body. Knowing and controlling the growth of hormonal substances in the body is very important, the health of the fetus and the woman herself depends on it. This allows you to prevent the occurrence of all kinds of pathologies and other complications that may appear and develop during pregnancy.

You must immediately understand that management of the entire period of pregnancy from conception to childbirth, observation and appropriate preventive procedures are the prerogative of qualified specialists. They can adequately assess the condition of the woman and the fetus and indicate the further actions that need to be taken to prevent deterioration in health for both.

Therefore, all recommendations coming from the doctor must be followed with the utmost precision. This will be much easier if the woman herself is informed about the results of the tests performed and fully trusts the doctor’s opinion.

In some cases, during standard health tests, the presence of human chorionic hormonal substances is detected, which makes it possible to establish the fact of pregnancy. Early diagnosis is based on the fact that a week after fertilization, a noticeable increase in the volume of hormones in the body begins, among which is hCG. If this happens, the attending physician informs the patient about this. Analyzes and subsequent observations about the presence of hCG elements in the body should be carried out from the very process of conception until the end of the pregnancy, that is, childbirth.

HCG and Duphaston. influence.

Girls, I have a question, I took the hCG test at 10 DPO and it was 27.4, I immediately started taking Duphaston, I retested the hCG test at 15 DPO and it became 523, which seems to be increasing rapidly. I read options about the rapid growth of hCG, among them:

Multiple pregnancy (the level of the indicator increases in proportion to the number of fetuses);

Discrepancy between the actual and established gestational age;

Early toxicosis of pregnant women, gestosis;

Diabetes mellitus in the mother;

Chromosomal pathology of the fetus (most often with Down syndrome, multiple fetal malformations, etc.).

Taking synthetic gestagens.

So it’s the latter that interests me, duphaston is just a synthetic gestagen. so we came to my question, write down your hCG data and did duphaston affect his growth?

I took hCG twice - when I was admitted to the hospital for conservation and already at 12 weeks. In the first case, they wrote the hCG result (I don’t remember the number) and the phrase “hCG level is increased.” For a long time I puzzled over what and how. But the time was too short to draw any conclusions (as in your case). And, by the way, the baby turned out to be alone, without deviations. I wish the same for you.

Kiruska, thank you very much for your answer, and at what date did you take hCG for the first time? and when did you see the doll?

At 5 weeks, hCG was 11317. And we saw the baby and his heartbeat at 6 weeks. With hCG everything is so individual. ))) As my husband likes to repeat, “we will make decisions as problems arise.” So don't panic ahead of time. Everything is fine with you and your little one.

Kiruska, wow, this is hCG. and your husband says it right!

Somehow I don’t believe that Duphaston in its standard dosage of 1 tablet / 2 times a day can affect the rapid increase in hCG. I had anembryonia, hCG grew sooooo bad. At the same time, she drank Duf regularly, at some point the doctor even increased the dosage to 2 tablets / 2 times a day. but this did not affect the growth of hCG at all. I barely made it to a little over a thousand and began to fall.

Your growth is indeed rapid, but, to be honest, I have never taken hCG so early. see how he behaves next. and may everything be wonderful for you.