- August 26, 2019
- Pregnancy
- Zakharchenko Svyatoslav
An alternative to surgical abortion in early pregnancy is medical abortion. When performing an abortion with pills, the risk of mechanical injury to the birth canal is minimized, which means the risk of infertility is reduced. The earlier pregnancy is detected, the more effective and easier the abortion procedure will be. It is worth understanding which pills can be used to terminate pregnancy in the early stages.
Pharmaceutical abortion
Pharmaboration is carried out after examining the woman, undergoing an ultrasound examination, smear and blood tests. An ultrasound procedure will allow you to establish the fact of pregnancy, and a test will rule out inflammatory processes. The woman also donates blood to check the level of human chorionic gonadotropin, which is used to determine whether pregnancy has occurred. It is necessary to accurately determine the period, since abortion with pills is allowed only up to 42 days of amenorrhea. In another case, taking pills for miscarriage in early pregnancy will be fraught with consequences.
When undergoing a medical abortion, a woman is not recommended to visit a sauna, steam bath, or have sexual activity. This may cause increased bleeding. It is also necessary to refrain from physical activity and remain calm for several days.
Do I need to take tests or undergo an examination?
Regardless of the choice of method for interrupting the “interesting position”, you should consult a doctor and undergo a series of laboratory tests:
- Ultrasound to determine if you are late;
- analysis for hCG levels, if the situation with ultrasound is unclear;
- Rh factor, blood group test;
- tests for HIV, hepatitis, syphilis and other sexually transmitted diseases.
Do not delay in submitting the biological material that will be examined. The time for the drug procedure is an early period of up to 6 weeks. To speed up the process, you can contact the clinic for an express analysis service.
Contraindications
Abortion with any pregnancy pills in the early stages is contraindicated in cases of ectopic pregnancy, inflammatory diseases of the genital organs, uterine fibroids, pregnancy that occurred while using intrauterine contraceptives, as well as during pregnancy more than 42 days. Drugs used for abortion have a number of general contraindications:
- adrenal, renal, liver failure;
- anemia;
- violation of hemostasis;
- smoking in a woman over 35 years of age;
- porphyria;
- age under 18 years;
- lactation;
- bronchial asthma;
- long-term anticoagulant therapy;
- taking non-steroidal anti-inflammatory drugs.
If a woman needs an abortion during the lactation period, she is advised to stop breastfeeding for at least 14 days.
Sequence
Termination of pregnancy using medications requires more careful medical supervision of the patient than surgical methods of abortion. During the first visit to the doctor, a gynecological examination of the woman is carried out, pregnancy is diagnosed and its duration is established. A conversation is held about the advisability of the procedure (especially if it is the first pregnancy), the presence of contraindications, the peculiarities of the action of the drugs and the symptoms of an incipient miscarriage.
First stage
The patient, in the presence of a doctor, takes a mifepristone tablet and remains under observation for two hours. If she feels normal, the woman receives recommendations and goes home. At this stage, spotting and cramping in the lower abdomen may occur, which is normal.
Second phase
After 48 hours, a second visit to the doctor is necessary, where the woman undergoes an examination, a control ultrasound, takes prostaglandins (Mirolyut, Misoprostol, etc.) and is under observation for three to four hours. After this, in most cases, detachment of the fertilized egg occurs and it is expelled from the body. After a couple of days, the bleeding decreases, the pain gradually stops and the general condition returns to normal.
Control inspection
After 7-14 days, a repeat examination is necessary, during which the woman undergoes an ultrasound examination. If there are remnants of embryonic membranes in the uterus or ongoing pregnancy, vacuum aspiration or curettage of the uterine cavity is performed.
Menstrual function after the procedure is restored after a month, so a woman should approach the issue of contraception more thoughtfully. In general, in 95% of cases, medical termination of pregnancy takes place without any complications and allows preserving women’s reproductive health.
Stages of abortion
Medical abortion is carried out in several stages. First, the doctor prescribes a drug that inhibits the production of progesterone, the female sex hormone, as a result of which normal blood circulation in the uterine mucosa is disrupted, and it rejects the endometrium, along with the attached fertilized egg. Symptoms caused by the therapeutic effect of the drug are required, such as pain in the lower abdomen and spotting. If prolonged bleeding, repeated vomiting and pain that cannot be relieved by taking analgesics occur, you must immediately contact a medical facility. It is worth knowing which miscarriage pills to take and their dosage. Otherwise the consequences will be severe.
Mechanism of action of tablet drugs for abortion↑
Whatever the name of the medication abortion pill, almost all of them contain mifepristone. The mechanism of action of such medications is quite simple. Mifepristone is a substance that effectively suppresses the action of the hormone progesterone.
But the main function of progesterone is to maintain the existing pregnancy. As soon as the hormone loses its strength, it is interrupted. Here are some names and a brief description of the pills that can be used to perform a medical abortion.
"Mifepristone"
The first step uses drugs containing mifepristone, which is a synthetic steroidal antigestagen.
"Mifepristone", "Miropriston" (), "Pencrofton" (), "Mifeprex" (manufacturer - Moscow Pharmaceutical Factory) are Russian-made drugs, one tablet of which contains 200 mg of active substance. To terminate a pregnancy, the doctor prescribes 600 mg once, in three tablets. The drug is taken an hour after meals. The taste is neutral. After taking the tablets, you must be under medical supervision for at least two hours to avoid the development of severe side effects and to eliminate unwanted symptoms in a timely manner. Many women at this time complained of nausea, single vomiting, weakness, changes in blood pressure, dizziness, discomfort and pain in the lower abdomen. Most note the disappearance of side symptoms on the second day.
Tablets with a prescription in a pharmacy and without a prescription
Pills such as Postinor and Pencrofton can be easily purchased at a pharmacy without providing a prescription from a doctor; the price of such “abortion” pills is not high, but you shouldn’t get carried away with them either. Mifolian, Mifegin, Mifepristone and other similar drugs for abortion are also sold in pharmacies, but are available only with a prescription. Although, in our country you can certainly find pharmacies where you can buy them without a prescription, perhaps for an additional fee. But you shouldn’t buy them and take them yourself, because it’s risky. The gynecologist must select the appropriate drug.
"Misoprostol"
During the third day, Misoprostol is prescribed, which promotes the production of prostaglandins. As a result of taking the medicine, the uterus contracts and promotes the removal of the dead fetus. Misoprostol is a synthetic analogue of prostaglandin E, which provokes contraction of the smooth muscles of the uterus and dilation of the cervix. As an independent means for abortion, it is contraindicated and ineffective; it is used only in combination with the above-mentioned Mifepristone drugs. Taking pills to terminate early pregnancy is accompanied by cramping pain in the lower abdomen, confirming the process of contraction of the uterus. May cause allergic reactions. After taking the drug, the active substance begins to act within 30 minutes, abortion occurs within 6-7 hours, less often within a week. There are a number of contraindications when treating with Misoprostol:
- similar to those for taking Mifepristone;
- cardiovascular diseases;
- glaucoma;
- arterial hypertension;
- hormone-dependent tumors;
- use of intrauterine contraceptives.
Who is contraindicated for medical abortion?
A ban on this method of ending pregnancy may be imposed on women with diseases from the following list:
- abnormal course of pregnancy outside the uterus;
- disorders of the kidneys and adrenal glands;
- long-term use of corticosteroid medications;
- blood incoagulability;
- inflammation of the pelvic organs;
- myoma;
- scars after cesarean section, neoplasms in the form of tumors;
- allergic reaction;
- epilepsy; diseases of the heart and blood vessels, gastrointestinal tract and respiratory system;
- unwanted pregnancy with an intrauterine device while taking oral contraceptives.
Is this interruption effective?
The effectiveness of medical abortion is 82-86%. Two days after taking Misoprostol, the woman needs to undergo a repeat ultrasound. If the fact of death and expulsion of the fetus from the uterus is not confirmed, the woman must undergo a procedure for cleaning the uterus through surgery. In 4% of patients, after two weeks, blood clots and remnants of dead endometrium remain in the uterus. With increasing gestational age, this percentage increases. In this case, the doctor may decide to repeat the dose of Misoprostol. If you do not seek medical help in time, blood poisoning and sepsis may develop, and this, in turn, can lead to removal of the uterus and infertility.
Mifegin
The name of this drug is known to many, since it has long been actively used both in Russia and far beyond its borders. The essence of the action is to combat a group of hormones called progesterones. At the same time, Mifegin blocks uterine receptors, which causes rejection of the embryo.
Through gradual contractions and relaxations of the uterus, its cervix opens and the fertilized egg is released. Typically this process takes about eight hours. For greater effectiveness, the patient may be prescribed prostaglandins, but the simultaneous use of painkillers, even if they are non-steroidal, can significantly reduce the effect of the drug.
Today it will be possible to find a fairly large selection of analogues to Mifegin. However, it is among them that it is considered the most reliable means. The percentage of its effectiveness is almost 100, and the number of side effects is minimal, as is the likelihood of allergies.
Note. This remedy can have its effect only until the sixth week of pregnancy.
Before prescribing Mifegin to a woman, the doctor must exclude the possibility of ectopic fetal development through pelvic ultrasound. Depending on the individual characteristics of the patient, in rare cases the drug may have a negative effect. For example, the pregnancy will not be terminated, the dead fetus will not come out of the uterus, or excessive bleeding will begin. All this explains why it is unacceptable to perform abortions without a doctor.
The French-made drug is considered the most reliable means for terminating pregnancy up to six weeks. Its efficiency is close to 100%. Highly tolerable
Consequences
Medical abortion, like surgical abortion, can have undesirable consequences, which is why it is so important to carry it out strictly under the supervision of a doctor and after appropriate examination. An ultrasound examination will help rule out ectopic pregnancy. The use of drugs during an ectopic pregnancy can lead to rupture of the fallopian tube in which the fertilized egg is attached. This can lead to severe bleeding, pain and the need for emergency surgery. Treatment of ectopic pregnancy with tablets can be prescribed by a doctor if the pregnancy is short.
Pills to prevent pregnancy: are they necessary?
Pills to prevent pregnancy have become increasingly used nowadays. This is due to the fact that they have a minimal risk of developing complications, pregnancy after taking them occurs without any problems, as well as the relatively low cost of this type of abortion without significant harm to health. Thus, medical abortion has advantages over other types of abortion. And if you really have to resort to an abortion, then it is better to do it earlier without harming your body.
Reviews about medical abortion
Often, women who have undergone a medical abortion complain of hormonal imbalances, painful menstruation, cycle disruptions, thyroid problems, and weight gain. This is due to hormonal imbalance as a result of taking synthetic prostaglandin. Abrupt termination of pregnancy deals a blow to the body, which takes time to rebuild. Moreover, abortive drugs are aimed at suppressing one hormone and promoting the production of another. After an abortion, it is necessary to restore hormonal levels. For this purpose, long-term therapy with progesterone, a female sex hormone, is prescribed.
Nausea, vomiting and other manifestations of dyspepsia associated with taking Mifepristone may intensify against the background of early toxicosis of pregnant women, as well as with chronic diseases of the digestive system. To relieve symptoms, the doctor will prescribe an antiemetic with metoclopramide, such as Cerucal. If the symptoms are mild, the drug is taken in tablet form. For repeated non-stop vomiting, intramuscular or intravenous administration of the drug is indicated.
An increase in body temperature to 38 °C and its persistence for more than one day after taking Mifepristone may indicate the development of inflammatory processes in the uterus. If this symptom is detected, you should consult a gynecologist. The norm is to increase body temperature to 37.5 °C and maintain it for no more than two to three days. It is possible that the temperature may rise again after taking Misoprostol, which is considered normal within the same limits.
Such a complication as hematometra occurs quite often. Stagnation occurs in the uterus, a large volume of blood accumulates, which increases the risk of infection. This happens when Misoprostol has not worked, the cervix is not dilated enough to release the cavity, and the fertilized egg has died and tissue rejection has begun.
At the later permissible stages of an abortion, when taking pills to terminate an early pregnancy, closer to six weeks, women feel quite severe cramping pain. The longer the pregnancy, the larger the fertilized egg and the enlarged uterus accordingly. Contraction of the uterus in this case is a longer and more painful process than during a pregnancy of one week, when the fertilized egg is slightly larger than usual. Severe pain is also possible in nulliparous women and women with painful menstruation. If the pain is intolerable, the doctor may prescribe painkillers.
It is also necessary to be aware of such a complication as uterine subinvolution. That is, a slow contraction of the uterus to its normal size. It manifests itself as prolonged intense bleeding and the absence of cramping spasms in the lower abdomen. Over time, the color of the bloody discharge becomes brown. When these signs appear, symptomatic treatment is carried out. Tonic drugs are also prescribed to activate the muscles of the uterus.
Allergic reactions to pregnancy pills in the early stages are common, manifested by the appearance of various skin rashes (urticaria, dermatitis). The symptom goes away over time. If the patient has an allergic sensitivity to any component of the drug, but abortion is indicated, the doctor prescribes prophylactic use of antihistamines. Without their use, a woman is susceptible to severe allergy symptoms, including anaphylactic shock.
About 2-4% of medical abortions are ineffective. The fertilized egg does not die. The risk of uncompleted abortion is higher with increasing gestational age, as well as with multiple pregnancies. In this case, it is still recommended to interrupt it, because the use of drugs can cause the development of abnormalities and pathologies in the fetus. But it is not advisable to carry out a repeated abortion with medications; surgical intervention is necessary.
Sometimes a medical abortion is necessary for medical reasons, such as a high risk of spontaneous delivery, the risk of developing fetal pathologies, the presence of HIV diseases and syphilis in a pregnant woman, as well as various genetic, mental and oncological diseases. In case of unwanted pregnancy of girls under the age of 18, abortion is performed with medications in a hospital under the full supervision of doctors, with the written consent of the parents. In this case, a young and perhaps not fully formed organism will have fewer consequences than with surgical intervention.
Pros and cons of the drug method
Tablet abortion has the following advantages
• minimal risk of infection and injury to the uterus;
• the procedure can be carried out from the first day of a missed period;
• a woman recovers quickly after pharmaabortion;
• the effectiveness of the medicinal method is 95% and above.
Abortion using the pill has its downsides
• incomplete removal of the ovum in 4–8% of cases;
• high risk of bleeding from the uterine cavity;
• there is no complete guarantee of disposal of the embryo;
• a large number of contraindications and side effects.
Thus, if you decide to have an abortion, you have no contraindications, and the timing allows, then pharmaceutical abortion is the best choice. In any case, consult a gynecologist and do not self-medicate, because the consequences can be the most terrible!
To terminate an early pregnancy, you can use over-the-counter pills. To do this, you need to learn about the features of each drug, weigh the possible risks and prepare for potential side effects. Self-administered medical abortion requires a subsequent ultrasound examination to monitor the result.
What other pills can you take for miscarriage?
Emergency postcoital contraceptive medications are currently being produced and should be taken no later than 72 hours after unprotected intercourse. These are medications for miscarriage such as “Zhenale”, “Agesta”, “Ginestril”, “Ginepristone”. One tablet of this drug contains 10 mg of mifepristone. For emergency contraception, take 1 tablet two hours before or two hours after meals. The active ingredient in the drugs “Escaper” and “Postinor” is levonolgestrel. One Escaper tablet contains 1.5 mg. As with mifepristone, 1 tablet is taken to terminate an early pregnancy in the first 72 hours. If vomiting occurs within 3 hours after taking the tablet, the drug should be taken again. May cause cycle disruption and delay of menstruation by up to 7 days. The Postinora tablet contains 0.75 mg of levonolgestrel. A single dose per appointment is one tablet. Twelve hours later, take the second tablet so that the total dose is 1.5 mg of the active substance. If vomiting occurs in the first 3 hours after taking pills to terminate early pregnancy, the dose of the drug must be repeated. When using postcoital contraceptives, it is necessary to exclude previous pregnancy. In most cases, the drug does not cause side effects after taking it. Not recommended for regular use as contraception. Suitable for self-use at home, but only as prescribed by a doctor.
Having many side effects and complications, this type of abortion is considered gentle and has a number of advantages. First of all, the biggest advantage is that the procedure does not require surgery unless complications arise. The cervix and internal cavity of the uterus are not subject to mechanical damage, as during curettage or vacuum aspiration. The second big advantage is that abortion is performed on an outpatient basis, without hospitalization. Thirdly, there is no need for anesthesia. Ultimately, it is psycho-emotionally easier for a woman to tolerate taking a drug than an operation.
Tablets from China↑
Using abortion pills from China is a risky undertaking, even though they contain substances approved in Russia. Not every doctor will literally translate instructions from Chinese into Russian.
The only advantage of Chinese tablets is the low cost of the product. But is it customary to save on health? And will it be possible to minimize spending money if serious complications arise? Think again and again before buying such medications of questionable quality.
Without exception, all abortion pills have a common drawback: they disrupt blood clotting and hormonal imbalance!