Dicinone during pregnancy: reasons and methods of use


Composition of the drug

Dicynone consists of ethamsylate, a substance that has antihemorrhagic properties. It affects the cardiovascular system, normalizing capillary permeability, and stimulates the formation of substances responsible for blood clotting.


Dicinone is an effective hemostatic agent

Dicynone enters the pharmaceutical market in two forms: tablets for oral use and ampoules with solution, which are administered intramuscularly or intravenously. The drug is prescribed to pregnant women if the benefit from its use outweighs the risk of a possible teratogenic effect on the fetus.

Experts note the high effectiveness of the drug in stopping various types of bleeding, including uterine bleeding. Prescribing medication to a pregnant woman occurs only after a diagnosis has been established and under the supervision of the attending physician.

Indications for use and release form

Dicynone is indicated as a therapeutic and prophylactic agent for internal and external bleeding of various origins.

There are several ways to use it:

  • oral (inside);
  • intramuscular;
  • intravenous;
  • retrobulbar;
  • local (tampons and gauze bandages).

Dicinone is prescribed in the following cases:

  • to eliminate post-traumatic bleeding;
  • to prevent blood loss during surgery;
  • for diseases associated with bleeding (gynecological pathologies, cerebral infarction, lung and gastrointestinal diseases);
  • to prevent hemorrhages in premature babies.

dicinone in ampoules

In pharmacies the drug is presented in the form of tablets and ampoules.

The tablets are available in two versions: the dosage for children contains 0.05 grams of ethamsylate (active substance), and the dosage for adults contains 0.25 grams.

Packaging: 100 pcs. costs about 400 rubles. Ampoules are also presented in 2 versions: 12.5% ​​solution, 2 ml, 5% solution, 1 ml. A package of 50 ampoules costs an average of 650 rubles.

Indications for the use of Dicinon in the early stages

Scarlet or brown discharge at any stage of pregnancy can cause real panic in the expectant mother. If they are caused by reasons that can lead to termination of pregnancy (threat of miscarriage), the woman is prescribed Dicinon to stop the bleeding. Its use is justified for scarlet discharge caused by partial placental abruption (no more than 1/3). In this case, the pregnancy can be maintained.

Sometimes during pregnancy, a woman may experience more than just vaginal bleeding. This condition also requires the use of hemostatic drugs. With the help of Dicinonon it is possible to stop bleeding caused by:

  • surgical interventions in dentistry, ophthalmology, otolaryngology, gynecology;
  • systemic blood diseases;
  • emergency conditions (for pulmonary and intestinal pathologies);
  • hemorrhagic diathesis.


Dicynone is prescribed only by a specialist

The drug is often prescribed to pregnant women if they have hematomas due to chorionic detachment.

The chorion is the outer membrane of the fertilized egg, from which a full-fledged placenta is formed in the second trimester of pregnancy. In the first 16 weeks of pregnancy, the fetus receives nutrients through the chorion. Sometimes it happens that due to presentation (the peculiarities of the attachment of the fertilized egg in the uterine cavity), stress, high blood pressure, infection, injury, the chorion partially exfoliates. A hematoma (collection of blood) forms between it and the walls of the uterus. Gradually, the hematoma begins to resolve on its own. This is accompanied by discharge of scarlet or brown blood. With partial detachment of the chorion (placenta), pregnancy can be maintained. To stop bleeding, Dicinon is recommended, and maintenance therapy is prescribed. Treatment prognosis is positive. If the chorion (placenta) is completely detached, pregnancy cannot be maintained.

Gynecologists practicing abroad have ambivalent attitudes towards the prescriptions of their colleagues in the post-Soviet space. For example, in Canada, such medications are not used to treat this type of disorder.

The prescribed drugs are NOT used to treat hematomas. And even if they were prescribed to you, they did not help the hematoma disappear. All these drugs do not preserve pregnancy.

Berezovskaya E.

https://www.komarovskiy.net/faq/krovyanistye-vydeleniya-i-nalichie-retroxorialnoj-gematomy-v-9-nedel-beremennost.html

Dicynone can be prescribed according to indications in any trimester of pregnancy. Since in the first three months all the organs and systems of the child are formed, the drug should be taken with extreme caution. But if the doctor recommends it for treatment, then the threat of termination of pregnancy is higher than the potential risk of complications for the baby.

In the second and third trimester, medications are taken only under the supervision of a specialist.

Video on the topic “Komarovsky on maintaining pregnancy with the help of medications”

What is Dicynon

This drug has a pronounced hemostatic effect, in addition, it significantly strengthens blood vessels, both large and capillaries. Dicinone accelerates the process of platelet formation, and these blood elements have a very important function: they give it a certain stability, the ability to clot, protecting it from heavy bleeding.

Dicynone often becomes a kind of first aid during early pregnancy, since it is during these periods that the risk of miscarriage due to various external influences and diseases is quite high.

In addition to uterine bleeding itself, Dicinon is also used in the processes of placental abruption, as well as similar pathologies of the chorion - the outer membrane of the embryo. The chorion becomes a protective environment for the fetus in the very first days and weeks of its existence, and violations of its integrity pose a huge danger.

Contraindications and side effects

According to the FDA classification, the category of Dicinone is not defined, since no laboratory studies have been conducted that would completely exclude the absence of its teratogenic effect on the fetus. Therefore, the prescription of a medicine is indicated in cases where the benefits of taking it are higher than the possible consequences for the child.

The drug is contraindicated:

  • with thromboembolism;
  • with a tendency to form blood clots;
  • with increased vascular permeability;
  • in case of individual intolerance to the active substance.

Side effects are possible while taking the medication:

  • headache;
  • dizziness;
  • hyperemia;
  • nausea;
  • heartburn;
  • pain in the epigastric region;
  • hypotension.

Uncomfortable sensations during the period of taking Dicinon are a reason to consult a doctor

Side effects when taking Dicinone are rare. Most often they are associated with individual intolerance to the active substance etamsylate, a tendency to allergic reactions and in the presence of chronic diseases of the gastrointestinal tract. If at least one of the above side effects is observed while using Dicinon, stop taking it and immediately seek advice from a specialist. If an allergic reaction develops, you should call an ambulance, as anaphylactic shock is possible.

Dicynone is taken under the supervision of a specialist. It is also necessary to control blood clotting, since the drug belongs to coagulants.

Important: Dicinone is contraindicated for those women who continue to breastfeed their older child during pregnancy. When the drug is prescribed, lactation is stopped, as the medicine penetrates into the milk and is passed on to the baby.

Dicinone should not be combined with medications that thin the blood.

Dicinon for threatened miscarriage

Dicynone during pregnancy can be used in any of the situations in which it is necessary to stop bleeding or prevent it. More often, the drug is used when there is a threat of miscarriage, accompanied by vaginal bleeding.

Despite the fact that obstetrics has long and successfully practiced the use of Dicinon during pregnancy, the instructions for use contain little information about the harm of the drug to the unborn child. According to it, treatment can be prescribed in cases where the expected benefits outweigh the possible risks.

Doctors prescribe Dicinon not only for heavy bleeding, but also for barely noticeable discharge. This approach allows you to eliminate the problem in the early stages, without waiting for it to worsen.

If there is a threat of miscarriage, Dicinon should not be prescribed independently, since its administration is part of complex therapy. Without the proper approach to treatment, the drug will only “mask” the problem, aggravating the situation.

There is still no data on clinical studies revealing the effect of Dicynon on fetal formation. The decision about the need to take medication should be made by a doctor, and the entire course of treatment should be carried out under his supervision. Read more about the threat of miscarriage→

treatment for threatened miscarriage

Expectant mothers are usually prescribed Dicinon tablets during pregnancy; the dosage and duration of the course of treatment are selected individually. As a standard, it is recommended to take them 1 pc. three times a day at equal intervals. Duration of treatment – ​​at least 3 days.

Rules for taking for bleeding and other phenomena

The regimen for taking the drug, as well as its form, is prescribed by the doctor individually. According to the instructions for Dicinon, the daily dose is calculated from 10 or 20 mg of the drug per kilogram of weight. It is recommended for pregnant women in the form of tablets in three to four doses per day. Three hours after the tablet has been taken, Dicynon begins to act. The effect lasts for five hours.


The regimen for taking dicinone is selected individually by the doctor.

For heavy scarlet discharge, Dicinon is prescribed in the form of a solution. It is administered intravenously using droppers or intramuscularly. In this case, the active substance begins to work within 15 minutes.

The duration of treatment is determined by a specialist individually according to indications. After completing the course of treatment, the medication lasts for another 5–8 days.

If Dicinon is prescribed as a prophylaxis for post-surgical bleeding, its administration is indicated three hours before surgery. The dosage and form of application are selected by the doctor individually. Prescription is possible in any trimester of pregnancy according to indications and under the supervision of a specialist.

If there is a threat of miscarriage, Dicinon can be prescribed with various preparations of progesterone, magnesium, and vitamin E.

who took dicinone (etamsylate) at 5 weeks of pregnancy

murka | 05/11/2009, 13:13:42

They diagnosed a threat of interruption and prescribed me to take this medicine for 2 days. it is a hemostatic agent and is not said to be harmless; moreover, the instructions indicate that the safety of the drug during pregnancy has not been established. Tell me, who has already taken this medicine - what do you think about it?

  • 1. | 11.05.2009, 16:12:17
    I took dicinone at 5-8 weeks of pregnancy, now I’m already 28 weeks old, everything is ok. The medicine really helps, I consulted with two doctors, one in a private clinic. where I was kept under guard by another third-party doctor. Don't worry, everything was prescribed to you normally.
  • 2. | 11.05.2009, 22:41:02
    I have a blood disease, so when I have my period, I always take it for 9 years. There were absolutely no side effects.
  • 3. | 16.07.2009, 19:32:08
    Taken at 5 weeks of pregnancy with scarlet discharge. It's week 14 and there seem to be no consequences. I know a few more examples of people who used dicynon for bleeding during pregnancy - beautiful babies were born!!!!
  • 4. | 24.09.2009, 07:09:06
    I have 5 weeks. Due to a small detachment, they pose a threat. Dicinone is injected (dark brown discharge). Today is the second day, it seems to be helping, but at night my lower abdomen hurt a lot. I thought it was from the medicine, but the doctor said that no, the medicine couldn’t make me sick. I hope all be fine!
  • 5. | 26.09.2009, 19:42:38
    I started having beige discharge today... I’m 7 weeks old... the doctor told me to drink for 3 days, 1 tablet 2 times a day.. I hope everything will be fine
  • 6. | 05.11.2009, 17:25:56
    Good afternoon! I'm 7 weeks and started to have some light brownish discharge. On the ultrasound, the doctor said it was a detachment and prescribed 1 tablet of dicynon. 3 times a day, 3 days and bed rest, I hope everything will be fine because I trust the attending physician, and I wish everyone good health.
  • 7. | 17.04.2010, 17:06:55
    I was injected with it in the hospital three times a day for probably 5 days... although there was no detachment... then the daub started again - she prescribed it to me in tablets... after the daub disappeared it was stopped for 3 days... I was also worried that pregnancy was a contraindication...
  • 8. | 17.07.2011, 17:03:34
    At 5 weeks, spotting began, they injected platifilin and dicinone 2 times. in the house for 10 days, bed rest. At 14 weeks everything happened again, still dripping tranex. At 23 weeks the waters broke, artificial labor was induced..... and no one really explained anything, they said “this happens”
  • 9. | 26.09.2011, 11:09:07
    I’m also 5 weeks old and have a little spotting in the evenings, dark brown discharge and everything is clear, I don’t know what I’m doing, I’m injecting etamzilat and popoverine
  • 10. | 17.02.2012, 18:57:32
    Tell me, I’m planning a baby, but my periods take a long time. If I take dtcinon, will it interfere with conception?—?
  • 11. | 22.03.2012, 23:52:42
    At the seventh week, small brownish discharge began. The gynecologist told me to take Etamzilat. One tablet three times a day. I read that they are contraindicated for pregnant women and did not take them. I decided to consult with other doctors from another area... They said that Etamzilat is contraindicated for pregnant women to take and that it is not yet known how it can affect the fetus. And the daub in such periods can be repeated at the time when you should have menstruation. This happens. It even repeats two or three times during these periods. Since I had a daub not big, I decided to wait. And indeed, after a couple of days the smearing stopped. I was smeared for 10 days. Now, thank God, everything is going according to plan.
  • 12. | 11.04.2012, 21:47:20
    Hello, I can’t even imagine... I also have the so-called dark spot... In general, the period is short, two or three weeks... I came to confirm the pregnancy, when she saw my discharge, she got all scared and upset me. She says if you go to the gynecology now, They’ll give you an ultrasound and you’ll immediately have a miscarriage, frankly, isn’t it? Okay, at least she said....she prescribed this: 1.) Vikasol-1t-3 times a day; 2) Dicinon-1t-3 times a day; 3) ascorbic acid-6 dr., 3 times a day; 4) Magnum v6 - 2 t-by 2 r.d.; 5) valerian-3t-3 r.d.; 6) suppositories with Novacoin - 1-2 times a day……………..Please tell me, is there any reason to worry that I won’t harm my little one with this recipe? And the doctor was tortured that day…I just don’t know , what should I think... you read about these discharges, nothing comforting... please help me figure it out, if you know anything, answer.
  • 13. | 11.04.2012, 21:50:26
  • Anna
    And the course is 10 days... it turns out that in 10 days I’ll take 60 tablets of hemostatics alone...... it’s terrible, when I think about it...

    Anna, how are you feeling?

  • 15. | 02.05.2012, 11:48:40
    I’m in conservancy, they’re injecting me with papaverine, nosh-pu, etamzilat, everything is normal, so don’t delay, see a doctor right away
  • 16. | 17.07.2012, 14:23:08
    Dicinon is injected in maternity hospitals and is prescribed to pregnant women very often for scarlet or reddish discharge... with such, immediately go to the ambulance or to the doctor... the children of everyone I know were born healthy, and a small brownish daub may be not only due to the days of menstruation, but also because that the blood vessels can burst due to changes that occur in the 1st trimester, the doctor explained to me this way
  • 18. | 27.01.2013, 16:35:54
    4-5 weeks ago, a scarlet daub started two days ago, just a little, I went straight to the city in the residential complex, where I was immediately admitted to the gynecology department, today the daub is already beige, and I drink a little duphaston magnesium, Vit E, valerian, but they inject dicinone twice a day and Papaverine suppositories I’m lying upside down all day tomorrow for an ultrasound, God grant that everything goes well.

Analogues of the drug

In case of individual intolerance to Dicinon, discomfort or allergic reactions, the medication can be replaced with other drugs with a similar principle of action.

Comparative table of hemostatic agents

NameActive substanceRelease formContraindicationsUse during pregnancy
TranexamTranexamic acidTablets, solutionHypersensitivity, thrombosis, renal failureBleeding during pregnancy, chorionic detachment, for the prevention of bleeding during surgical interventions
EtamzilatEtamzilatTablets, solutionThrombosis, hemorrhageBleeding of various origins (if the benefit to the mother outweighs the risk to the fetus)
VikasolMenadione sodium bisulfite, synthetic vit.KTablets, solutionThromboembolism, hypersensitivity, hypercoagulationCoagulation disorders, hypoprothrombinemia. The last months of pregnancy to prevent bleeding in newborns.

Tranexam

It has a hemostatic effect and can penetrate the placenta.


Tranexam - prescribed for intolerance to dicinone

Etamzilat

The main active ingredient of Dicinone.


Etamzilat is an effective hemostatic agent for bleeding of various etiologies.

Vikasol

A drug based on synthetic vitamin K, which has a hemostatic effect.

Vikasol - prescribed for the treatment and prevention of bleeding

Do Dicynon have any side effects?


Basically, the drug is well tolerated, so some manufacturers note in the attached instructions that it does not have any side effects, in individual cases only allergies. But there are still other consequences that occur quite rarely, but can still occur in a pregnant woman. Side effects of taking Dition include:

  1. From the nervous and also central systems: headache, circulatory disorders, dizziness, numbness of the extremities of the arms and legs.
  2. From the gastrointestinal system: heartburn, heaviness in the abdomen and nausea.
  3. From the cardiac system: drop in blood pressure. In such cases, not enough oxygen reaches the brain, which causes fainting and dizziness.
  4. Allergic reaction. As a rule, a rash appears on the skin; in rare cases, there may be swelling.

Many women are concerned about thrush during pregnancy, but it has nothing to do with taking this drug, as many people think. Due to the fact that the body of the expectant mother is being rebuilt, a hormonal imbalance occurs, the consequence of which may be disruption of the vaginal environment. Having a large number of advantages, Dition is used only when there is a real threat of fetal loss. Only a leading gynecologist, based on tests, can decide whether the drug is worth using and whether the risk of using the drug exceeds the risk of losing the child.

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