Is Epigen spray safe for the fetus: complete information

The pregnant woman's body is constantly exposed to external factors. It is easy for viruses, bacteria and fungi to penetrate inside, because a woman’s immune system is weakened.

Diseases of the reproductive system are especially dangerous, because pathogens can penetrate the uterine cavity, causing defects in the development of the fetus, and sometimes even causing miscarriage or premature birth. This condition requires certain treatment.

What medications can be used during gestation? The intimate remedy Epigen is one of those medications that are often prescribed to women even in the early stages of pregnancy.

Forms of release, composition and action of Epigen intimate products

The main component of Epigen Intima is a natural extract obtained from the rhizome and licorice root. In medical terminology it is called glycyrrhizic acid.

The product contains herbal components, which together effectively resist sexually transmitted infections. Varieties of Epigen are presented in the table.

Unusual possibilities of ordinary licorice

One of the most favorite plants from the green pharmacy arsenal is licorice. Its healing “abilities” are also widely used by traditional medicine. This plant activates the body's immune forces, preventing viruses and other infections from destroying human health. Its root contains a potent element - glycyrrhizic acid. Scientists have found that it is effective against the herpes virus, papilloma, and cytomegalovirus. The pharmaceutical company decided to use this unique property of licorice to produce the Epigen Intim series of products. Moreover, the specialists of this company found a way to enhance the therapeutic capabilities of glycyrrhizic acid: they created “activated licorice.”

Epigen in the form of a spray has been used in gynecology (including during pregnancy of patients) for more than ten years. It is used externally, effectively relieves inflammation, stops the development of viruses, accelerates tissue healing, has an antipruritic effect, and promotes the production of its own interferon. Since this drug is created on the basis of natural ingredients and is applied topically, it does not enter the systemic bloodstream and does not affect the course of pregnancy and fetal development. Therefore, it is often prescribed to women carrying a baby, even in the 1st trimester.

Indications for use

Epigen spray during pregnancy is prescribed if the patient is diagnosed with pathogenic microflora in the vagina during examination. The medicine is used as a separate drug or in combination with other drugs, it all depends on the type of pathology. Epigen Intim is effective for:

• herpes simplex,
• candidiasis (thrush),
• vulvovaginitis,
• papilloma virus,
• herpes zoster,
• erosion and inflammation of the cervix,
• bacterial vaginosis,
• cytomegalovirus.

How will he help?

According to obstetricians and gynecologists, when prescribing Epigen spray during pregnancy, its duration is not critical. It is allowed to be used in the early stages and just before childbirth. The safety of the drug for this category of patients has been confirmed by clinical trials conducted at the Research Institute of Obstetrics and Gynecology in St. Petersburg.

The spray is indicated for the treatment and prevention of ailments caused by HPV, herpes virus, cytomegalovirus, vulvovaginal candidiasis, nonspecific colpitis and bacterial vaginosis, as well as for the prevention of erosions, ectopia, dysplasia, and condylomas.

Contraindications and limitations of use

The drug is natural and does not contain plant extracts, so there are no contraindications to its use. The only contraindication is individual hypersensitivity to the active substance or auxiliary components.

In some cases, a reaction may occur in the form of allergic rashes (urticaria, swelling, rash). Before using Epigen during pregnancy, it is recommended to conduct an allergy test.

To do this, you need to apply a little product on your wrist and monitor the condition of your skin throughout the day. If redness, itching or rash appears, you will have to choose another medication.

Epigen Intim price, where to buy

The pharmaceutical drug cannot be classified as cheap, but the evidence of therapeutic effects and production in Spain is really worth the money. In the Russian Federation, the price of Epigen Intim spray starts at 600 rubles - for such a minimum price a 15 ml bottle is purchased. You can buy a spray in a 60 ml bottle for between 1100 and 1500 rubles - this form of the drug may be required, for example, for thrush due to a decrease in the body’s own immune parameters. In St. Petersburg, the drug is distributed by the Ozerki Pharmacy - intimate hygiene gel can be purchased from the distributor for an average of 650 rubles.

The price of Epigen intimate spray in other post-Soviet countries may vary not only from the form and quantity of the drug, but also from the place of purchase, since some pharmacy chains enter into individual contracts with foreign suppliers. Ukraine demonstrates this situation: in first place is Dnepropetrovsk, where a 60 ml cylinder can be purchased for 400 hryvnia. Next comes Kharkov - the price of a spray for intimate hygiene is 460-480 hryvnia, and you can buy a spray in Kyiv for 500 hryvnia. The price of Epigen Intim gel is the same throughout almost the entire country and is about 300-350 hryvnia.

In Belarus, a medicinal spray with a capacity of 15 ml can be purchased for 370,000 BYN. rubles The price of intimate hygiene gel is almost 2 times less and in Minsk is about 170,000 BYN. rubles Such a large difference in the cost of various pharmaceutical forms of Epigen Intim is justified by the scope of application, because the gel is used mainly for everyday hygiene procedures, and the spray is prescribed for therapeutic purposes by qualified medical specialists.

You should find out how much a medicine costs in Kazakhstan yourself, since there is no reliable data provided by licensed points of sale.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Epigen intimate gel 250mlCHEMIGROUP FRANCE
  RUR 899 order
• Epigen Intim spray for local use. and outside approx. 0.1% 60ml Cheminova/B. Brown Medical S.A.

  RUB 2011 order

• Epigen Intim spray for local use. and outside approx. 0.1% 15ml Cheminova/B. Brown Medical S.A.

  999 RUR order

Pharmacy Dialogue

• Epigen Intim spray 60mlB.Braun

  RUB 2,112 order

• Epigen Intim spray 0.1% 15mlB.Braun

  RUB 1,065 order

• Epigen Intim gel for intimate hygiene 250ml Cheminova

  RUB 1,143 order

Europharm* 4% discount using promo code medside11

• Epigen intimate spray 0.1% 15 mlHeminova International S.A./B.Brau

  1230 rub. order

• Epigen intimate gel for intimate hygiene 250 ml Hemigroup France

  RUB 1,119 order

• Epigen intimate spray 0.1% 60 mlHeminova International S.A/B.Brown

  RUB 2,287 order

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PaniPharmacy

• Epigen intimate gel 250ml Ukraine, Heminova
  404 UAH. order

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Is it safe to use the drug during pregnancy?

Epigen intimate spray and gel are used topically. With this use, the active substance is not absorbed into the general bloodstream, and therefore does not cause negative reactions in the fetus. The drug is used not only for the treatment of sexually transmitted infections, but also for the prevention of unwanted manifestations. In this way, relapses of chronic pathologies of the reproductive system can be prevented.

Scientists who have conducted experimental studies on animals confirm that glycyrrhizin does not have a mutagenic effect on the fetus during the perinatal period. From the experience of using Epigen by pregnant women, it is believed that the product is quite effective and at the same time safe.

Reviews about Epigen

Reviews of Epigen Intim spray characterize the pharmaceutical drug on the positive side. Patients with various infectious diseases of viral etiology recommend the drug on thematic forums and Internet resources, because the spray allows you to eliminate the pathological focus of the nosological unit and normalize the functioning of the genital organs and skin. For thrush, the medicine allows you not only to get rid of unpleasant discomfort and odor, but also to avoid this problem in the future, since the intimate gel effectively prevents this disease.

The anti-condylomas spray, in combination with surgical treatment, completely neutralizes the human papillomavirus, which ensures rapid healing of the skin defect and the fight against further relapses. The spray for HPV activates the humoral and cellular immunity, allowing you to further recognize the structure of the pathological agent and eliminate possible re-infection.

The pharmaceutical drug also helps with bacterial and nonspecific inflammatory diseases of the genital organs. An intimate spray allows you to maintain a physiological level of acidity, providing a feeling of cleanliness and freshness. Thanks to the drug Epigen intimate, the genital area of ​​both partners is protected from unpleasant consequences in the form of irritation, redness or other natural reactions.

Reviews from doctors are based primarily on the pharmacological effects and duration of the course of conservative therapy. Both indicators of a drug in the form of a spray allow us to give professional and qualified preference, based on reliable clinical studies, to this drug. On thematic resources, some medical professionals even openly admit about the independent use of Epigen Intim, which cannot but tip the scales in favor of the medicinal spray.

Separately, it should be noted reviews of Epigen Intim gel, which is often used incorrectly. The cream is designed to keep the genitals clean during daily intimate hygiene, unlike a spray. Of course, both pharmaceutical forms of the drug are based on licorice root extract, but the gel has a milder effect. The absence of soap and some other auxiliary components allows the gel to be used exclusively for cosmetic purposes.

This dosage form receives good recommendations from women who are carrying a child. Gel during pregnancy allows you to avoid a large number of aesthetic consequences of this physiological process, caused by changes in hormonal levels and some other features of the female body. The chemical formula of Epigen cream is specially designed for daily care, which in practice is manifested by the absence of dryness and various types of irritation after its use.

The price of the intimate gel is indicated below, but it is worth noting that among hygiene products it is the best, because it contains a plant with therapeutic properties. Licorice root has long been used for medicinal and cosmetic purposes, which creates a certain level of trust in this pharmaceutical drug, which is why women tend to choose an experienced method of daily intimate hygiene.

Directions for use

Epigen spray is prescribed exclusively by a doctor for medical reasons. This is especially important in the first 12 weeks of pregnancy. The spray is used not only externally, but also intravaginally. Depending on the type of pathogen, the specialist selects the dosage and frequency of use of the medication individually for each patient. The treatment plan may be as follows:

• for infection caused by cytomegalovirus or herpes simplex - up to 5 times a day, 2 weeks,
• for bacterial diseases (vaginitis, candidiasis) - 4-5 injections per day, 10 days,
• for severe itching, burning and other discomfort - twice a day (in the morning and before bed), up to 6 weeks,
• for sanitizing the genital tract shortly before childbirth - 6 times every 24 hours, about a week.

In order to spray the solution correctly, you need to study the included instructions. Treatment will be effective if you adhere to the basic recommendations for the correct use of the drug:

• before injection, you need to wash yourself with warm water using an intimate hygiene product, then blot the external genitalia dry with a towel,
• Shake the canister with the solution well and spray it into the desired place so that it is at a distance of no closer than 5 cm and is in a vertical position,
• when used intravaginally, put on a special tip and lie on the bed, insert it deep into the vagina and spray the medicine,
• in the latter case, it is recommended to lie down for about 5 minutes so that the medicinal solution is distributed inside and has time to act, while your legs should be raised up.

After each intravaginal use of Epigen, it is recommended to wash the nozzle in a soapy solution, dry it and only then put it in the box. During subsequent injections, the tip must be rinsed with boiled water.

Features of the action

You should know that Epigen Intim spray does not have a direct antimicrobial or antifungal effect. It is unable to destroy the pathogen on its own.

In relation to viruses, the mechanism of its influence is quite complex. Glycyrrhizic acid is a stimulator of the synthesis of interferon, a natural antiviral agent. In addition, it inhibits the replication of the virus, which is why it cannot penetrate cells.

However, candidiasis and other diseases are included in the list of indications for treatment with Epigen spray. But in the instructions, the manufacturer indicates that the drug can be used for such diseases, but only as an adjuvant, as part of complex therapy.

It effectively eliminates the symptoms associated with the inflammatory process - pain, itching and irritation, due to which the expectant mother quickly begins to feel better. But this does not eliminate the need for simultaneous administration of specific antifungal drugs or acyclovir.

If Epigen spray is used as a prophylactic agent, it may well be prescribed as monotherapy. Stimulation of local defenses leads to long-term remission of diseases such as candidiasis and genital herpes.

This remedy is also very effective for inflammation after sex. It allows you to quickly get rid of itching and pain, and accelerates the healing of abrasions. The same applies to the treatment of nonspecific vulvovaginitis.

Analogues approved for pregnant women

In case of individual sensitivity to the constituent components of Epigen or for another reason it is impossible to use it, specialists prescribe another drug (analogue) identical in its effect. Among the analogues approved for use during gestation are:

1. Candide (solution, gel, tablets). The active ingredient is clotrimazole.
2. Genferon (vaginal suppositories). The active substance is human interferon.
3. Terzhinan (tablets for vaginal use). The composition includes ternidazole, nystatin.
4. Panavir (suppositories, gel, spray). The active ingredient is a complex of saccharides (glucose, mannose, arabinose, galactose, xylose).
5. Pimafucin (suppositories, tablets, cream). Contains natamycin.

Compound

100 ml spray for topical use contains:

• glycyrrhizic acid – 0.1 g (the amount of the active component is equivalent to ammonium glycyrrhizinate);
• malic acid;
• fumaric acid;
• ascorbic acid;
• folic acid;
• propylene glycol;
• Tween 80 (polysorbate 80);
• purified water.

Composition of Epigen Labial (corresponds to gel for external use):

• ammonium glycyrrhizinate – 100 mg per 100 ml (active component concentration – 0.1%);
• Apple acid;
• fumaric acid;
• ascorbic acid;
• Polavax GP 200 (cetearyl alcohol-Peg-20 stearate);
• phenonip;
• butylated hydroxytoluene;
• flavor 195 AG;
• distilled water.