Furadonin during pregnancy: safety of the drug at different stages

For pregnant women, antimicrobial agents to relieve inflammation are prescribed quite often. The percentage of expectant mothers who come in with cystitis, pyelonephritis, pyelitis and other infectious processes in the urinary tract is more than 40%.

This issue becomes relevant due to surges in hormone levels, a decrease in general immunity, and pressure from the growing uterus on the bladder, which provokes the accumulation and stagnation of urine with its further infection. If the identified causative agent of the disease is sensitive to Furadonin, it is prescribed, despite the fact that pregnancy is included in the list of contraindications to it, why is this?

Furadonin is not an antibiotic


This is a synthetic drug with an antimicrobial effect, based on nitrofurantoin.
Metabolism of this medicine occurs in the intestines, and not in the liver, like most antibiotics.

From the intestines, the lymph current spreads throughout the body and blocks the spread of infection.

The main substance accumulates in the urine, thanks to which it is effective against diseases of the bladder, ureters and kidneys, and after 3-4 hours it is already excreted from the body.

The fact that this drug has a spectrum of action that is not inferior to that of antibiotics, with fewer side effects, makes its use more preferable for pregnant women.

Video on the topic

    During pregnancy, my doctor also wanted to prescribe Furadonin, but I read the instructions and was scared by the contraindications and the fact that this drug is not advisable to take during pregnancy.

During pregnancy, the female body experiences enormous stress associated with hormonal changes and decreased immunity. A minor cold or hypothermia can cause inflammatory diseases of the genitourinary area. One of the most common among them is cystitis. The possibility of infection from the intestines entering the urinary organs, accompanied by pressure on them from the growing uterus, significantly increases the risk of inflammation. The question of whether it can be used during pregnancy to treat cystitis often arises in women who experience symptoms of bladder inflammation. The instructions for use indicate the period of bearing a child as one of the contraindications.

Traditionally, Furadonin is prescribed for cystitis. This drug effectively copes with many types of pathogens of infectious diseases.

Instructions for use indicate the period of childbearing as one of the contraindications

Indications and contraindications during pregnancy

Despite the favor of doctors towards the drug, it should not be taken from the second to the twelfth week of pregnancy inclusive.
Strictly! The ban is based on the fact that the active substance is able to overcome the placental barrier and negatively affect the growth and development of the fetus, which is fundamental and intense during this period.

Indications for the use of Furadonin during pregnancy should be based on the result of bacterial culture, which showed that the pathogens are sensitive to it. Taking a drug without a test result is risking your health and that of your child.

Possible consequences of taking

For the fetus:

  • Development of hemolytic anemia: destruction of red blood cells that provide oxygen delivery to internal organs. This is an extremely dangerous condition, since the tissues are not only not supplied with oxygen, but are also subject to destruction by indirect bilirubin, released in huge quantities during the destruction of red blood cells.
  • Disorders of intrauterine development: disproportion of body parts, defects of internal organs

For mother:

  • From the respiratory system: compressive pain in the chest, shortness of breath, attacks of bronchial asthma in the presence of the disease.
  • From the digestive system: lack of appetite, vomiting, attacks of nausea, diarrhea. In cases of weakened liver, hepatitis may develop.
  • From the nervous system: headaches, lethargy, feeling tired.
  • From the hematopoietic system: a decrease in the number of leukocytes, leading to weakened immunity, platelets, reducing blood clotting, the development of anemia.
  • Allergies: Quincke's edema, skin rash.
  • Other: fever, joint aches, flu-like.

The absorption of Furadonin increases when taken with food or combined with medications that delay the release of food mass from the stomach. Therefore, it is better for pregnant women to take it separately.

How to reduce the risk of negative consequences

Follow these guidelines:

  1. Take Furadonin as prescribed by a doctor, based on an analysis of pathological flora.
  2. Take each dose of medication with a glass of clean water.
  3. Do not delay emptying your bladder.
  4. Take a repeat flora test after 3 days of taking the medicine, if it shows that the acute inflammation has been relieved, switch to herbal remedies or homeopathic remedies. After consultation with your doctor!
  5. Use the drug only after 12 weeks of pregnancy.

General information about the drug

In the pharmacy chain you can find the drug in 2 release forms. Most often, Furadonin is sold in the form of tablets; they are small in size and coated.

But there is also a powder intended for oral administration. It is diluted with liquid. However, the medicine is rarely found in powder form.

The instructions attached to Furadonin prescribe that this drug is classified as a group of medications with pronounced antibacterial and bactericidal properties. Moreover, the drug itself is not an antibiotic in the usual sense; it belongs to the group of nitrofurans.

The active substance is nitrofurantoin, it is produced in the format of tablets containing 100 or 50 mg of the active substance, enteric-coated. Mostly used to treat urinary tract and bladder infections. Moreover, for such a disease as cystitis, it is practically not prescribed due to its side effects. But in any case, its purpose, dosage and course of treatment should be determined by a doctor.

Reviews

Furadonin, like all drugs, has two categories of reviews: “helped” and “did not help.”
In cases of ineffectiveness of the drug, most likely, it is taken at random, without analysis or medical prescription.

Those who found the drug useful note its rapid action - after 3 days there was a significant improvement, no side effects.

Those who were helped by Furadonin over a longer period - 7 days - noted nausea, vomiting, pain and aching joints similar to a flu-like condition.

The drug has a relatively low cost and acts more mildly than its domestic analogue Furagin.

Although it is not advisable to take any medications during pregnancy, there are situations when it becomes necessary. Cyston during pregnancy: indications for use, as well as reviews of women about treatment.

Read about how to relieve pain from cystitis here.

And here https://mkb2.ru/tsistit-i-mochevoy-puzyir/u-zhenshhin/tabletki-ot-cistita.html all about the treatment of cystitis in women with the help of medications. The effect of drugs on the body.

Side effects

Against the background of long-term or incorrect use, the likelihood of developing side effects increases, these include:

  • disturbances in the functioning of the digestive system with the development of diarrhea;
  • headaches, dizziness, confusion;
  • nausea, vomiting;
  • with long-term use, disturbances in the functioning of the central nervous system.

Furadonin with long-term use can cause neuropathy. Against the background of which the transmission of impulses is disrupted, convulsions and numbness of the limbs occur.

Is Furadonin possible during pregnancy: results


Furadonin is far from the most toxic drug in terms of its effects on the liver and kidneys.

Its effects on fertility (the ability to reproduce) have only been studied in animals and indicate a potential risk to the fetus.

Clinical studies (taken by pregnant women) have not confirmed this risk, but since it was initially identified, the drug is included in list B and is contraindicated during pregnancy.

Domestic medical practice does not know of cases of direct negative effects on the fetus and the occurrence of malformations after taking Furadonin, so it is often prescribed by doctors.

Start treatment with a test, take the medicine if prescribed by the doctor, follow the rules of administration and inflammatory diseases will recede without causing harm to you and your unborn child!

Due to hormonal changes in a pregnant woman, her body becomes more susceptible to certain diseases. Cystitis during pregnancy: symptoms of acute and chronic inflammation, laboratory diagnosis of the disease.

Read about the features of selecting drugs for the treatment of cystitis in women in this material.

Instructions for use

The instructions for this drug state that it is contraindicated during pregnancy. Although medications in this category are used in the treatment of expectant mothers, the risk of negative effects on the fetus is quite high. Therefore, the treatment process is carried out after a microbiological study, as a result of which infectious pathogens are detected and their sensitivity to the antibacterial drug is determined.

But still, under no circumstances should you take Furadonin during pregnancy before 12 weeks. Since this is when the formation of the main organs begins and the fetus during this period is very vulnerable to external influences. In the first week, the embryo receives all the necessary substances from the fertilized egg. It develops autonomously and is not associated with the mother's body. During this time, the fertilized egg moves in the tube to the uterus and already on the 7th day sticks to its wall. After this, a common bleeding is formed between the mother and the fetus, through which both nutrients and toxic substances are supplied. But after 12 weeks, all organs are practically formed and the external influence on them is not so significant. Therefore, it is possible to use Furadonin at this stage of pregnancy. But it must be prescribed and under the supervision of a doctor, who will compare the risk of its use with the risk of developing urinary tract infections.

Indications and contraindications for the use of Furadonin

Pregnant women very often develop pyelonephritis, cystitis, and they are also very prone to other urinary tract diseases that are caused by infection. For the effective treatment of these diseases, Furadonin is prescribed. Especially in cases where the infectious agents are not sensitive to other drugs. Contraindications to its use are diseases of the heart and vascular system, disorders of the kidneys and other organs, as well as hypersensitivity to Furadonin or some of its components.

Side effects from taking

Taking this drug in some cases may be accompanied by various side effects. These include shortness of breath, chest pain, decreased appetite, diarrhea, nausea, vomiting, severe headache, damage to lung tissue, toxic liver damage, decreased platelet or white blood cell counts, anemia, lethargy, urticaria, itchy rash, fever, angioedema, joint pain, etc. Due to the side effects and negative effects listed above, Furadodin should not be taken by pregnant women, and in case of any diseases it is necessary to consult a doctor. Only he can assess the risk of the disease and prescribe the necessary treatment with the least risk for the development and health of the unborn baby.

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