Anaprilin during pregnancy - indications and contraindications, possible health risks || Is it possible to use anaprilin during pregnancy?

Anaprilin is a drug that is widely used in modern medicine as an antihypertensive drug - a medicine that lowers blood pressure. The drug is used for severe pathologies of the cardiovascular system - hypertension, arrhythmias and angina pectoris.

The drug effectively stops heart attacks, restoring a person’s well-being. However, the drug has a number of side effects. During pregnancy, anaprilin provides a systemic effect on the woman’s body, so it is not advisable to use it.

Use in early pregnancy

Anaprilin is a drug that belongs to the group of adrenergic receptor blockers. The main effect of the drug is that it prevents adrenaline from binding to its receptors.

The following effects occur:

  • the heart rate and blood circulation rate decrease;
  • blood pressure decreases.

Taking the drug is accompanied by a slowdown in blood flow through the mother's vessels. And since the fetus and mother are directly connected through the vessels of the placenta, the child’s oxygen supply is reduced due to a decrease in the speed of blood flow.

A condition called “fetal tissue hypoxia” occurs. It is considered one of the most severe complications occurring during pregnancy.

In addition to indirect effects through the mother’s body, Anaprilin during early pregnancy also directly affects the fetus. The drug passes through the barrier of the placental blood flow and penetrates the tissues of the embryo. In it, it affects only the developing organs and systems. And if the body of an adult patient is able to withstand such an impact and benefit from it, then it can cause harm to the fetus.

It is not recommended to use the drug in the early stages of pregnancy.

Briefly about the drug and mechanism of action

This medicine is one of the five drugs that are most often used for vegetative-vascular dystonia. Usually people use Anaprilin for panic attacks and fear, because the drug is inexpensive, quickly helps relieve anxiety, lowers pulse and lowers blood pressure. However, Anaprilin is not so harmless.

Its active ingredient is propranolol. Anaprilin belongs to the group of beta-adrenergic blockers, that is, it blocks the functioning of beta-adrenergic receptors in various organs. These receptors are located at the connections between nerve fibers and organs. They react with excitement to adrenaline, the fear hormone. Excitement itself leads to an increase in the production of this hormone. A large amount of adrenaline in the blood contributes to panic attacks. Simply put, when fear arises and adrenaline is released, a chain reaction occurs. And the drug Anaprilin makes beta-adrenergic receptors insensitive to adrenaline and blocks them. Then it turns out that after excitement and fear there is a lot of adrenaline in the body, but it cannot affect a person, because Anaprilin has closed all organs for him. It is this effect of the medicine that calms and relieves a panic attack.

Anaprilin, however, is not a sedative or psychotropic drug. With vegetative-vascular dystonia, you need to quickly neutralize the effect of adrenaline on the body. Anaprilin is quickly absorbed into the body, its effect begins in 3-5 minutes if it is placed under the tongue. It reaches its maximum effect an hour and a half after administration. The effect of the medicine lasts up to 5 hours. Anaprilin is sold in the form of tablets of 10 and 40 mg.

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The main effect of the drug is to lower the heart rate, reduce the conductivity of nerve impulses, lower blood pressure, and reduce the heart's need for oxygen.

In the later stages

In the later stages of pregnancy, the listed side effects are accompanied by another formidable complication - the threat of miscarriage. During pregnancy, anaprilin affects receptors that are located not only in the heart and blood vessels, but also in the woman’s uterus. Its effect leads to the fact that muscle tone in the organ increases significantly. The uterus begins to contract rhythmically.

Increased contractility of the uterus can cause the mother to have a miscarriage. If the process is not stopped in time, the birth of a premature fetus is possible. It is not recommended to use Anaprilin during late pregnancy (up to 28 weeks), since the child’s body is not yet ready for independent existence, the fetus is not yet full-term.

Premature birth is a huge risk for the baby’s life, despite the achievements of modern neonatology.

The risk of developing such serious complications makes it possible to unambiguously answer the question of whether anaprilin can be taken by pregnant women in later stages.

Classification of hypertension in pregnant women

Anaprilin during pregnancy - reviews on the use of the drug

Despite the rather serious restrictions on the use of the drug, reviews from women who used Anaprilin during pregnancy are generally positive. It is worth noting that the drug was prescribed exclusively in situations where other methods could not correct the pregnant woman’s condition. The most common indication (according to reviews) is arterial hypertension (high blood pressure).

To summarize, it is worth saying once again that Anaprilin during pregnancy is the drug of last choice. The medicine can only be prescribed by a doctor, no self-medication. The dosage is determined by the doctor in each case individually. The doctor also monitors the woman’s condition during therapy.

Is it possible to use Anaprilin while breastfeeding?

Anaprilin belongs to a group of drugs that penetrate into milk. If the instructions are not followed, Anaprilin enters the child's body during breastfeeding and affects his blood circulation.

The child’s heart and blood vessels have their own characteristics, their sensitivity to harmful influences is higher, so the newborn may experience pathological symptoms: slow heart rate, too low blood pressure. This adversely affects the baby and leads to the development of serious disorders.

Side effects of Anaprilin and contraindications

Anaprilin has a number of side effects. The drug lowers blood sugar, increases the contractile properties of the uterine muscles, enhances the motility of the gastrointestinal tract, provokes spasm of peripheral vessels, and reduces the speed of responses.

Anaprilin also has contraindications. These are bradycardia and decreased intracardiac conduction, hypotension and heart failure. In case of heart disease, Anaprilin can even cause pulmonary edema. This medicine should not be used if you have bronchial asthma or diabetes mellitus, as there is a risk of hypoglycemic coma. It is strictly prohibited to take Anaprilin during work that requires special attention. For example, when driving public transport.

Reviews

The opinions of expectant mothers regarding whether Anaprilin can be taken during pregnancy are clear: the drug should be taken only if it has been prescribed by an experienced cardiologist. Only a high-level specialist can assess the patient’s condition. He must weigh the risk to the mother's life against the risk of complications to the baby.

If a pregnant woman has a serious pathology - severe hypertension, arrhythmias, which can be complicated by coronary artery disease, then she should continue taking the medicine. The doctor selects the dose individually in each case.

Reviews of Anaprilin during pregnancy can be positive: most newborns do not experience any problems after birth. However, it is worth considering that the risk of complications is very high, and the child’s health is at great risk when taking the medicine.

Use of Anaprilin by pregnant women

Women during pregnancy can use Anaprilin for treatment only on the recommendation of a doctor and under supervision. The drug can cause hypoxia of the child inside the womb. The drug reduces blood pressure and reduces heart rate. This negatively affects the child.

But if the mother has severe hypertension, the risk of brain pathologies in the child increases. For this reason, when prescribing Anaprilin, the importance of preserving the woman’s health, and then the baby’s health, is always assessed. The drug is dangerous during any stage of pregnancy. You should not use Anaprilin during lactation to avoid possible risks.

Reviews of the treatment of hypertension in pregnant women can be seen in the video:

Is Anaprilin harmless?

The drug is not absolutely safe. The main active ingredient is propranolol. Anaprilin is a beta-adrenergic blocking drug that stops the function of beta-adrenergic receptors. These receptors are located at the junctions of nerve fibers. Show excited reactions to the action of adrenaline.

Danger

Excitement itself causes an increase in the production of this hormone. A large amount of adrenaline in the blood can cause panic attacks. If fear occurs, accompanied by the release of adrenaline, a chain reaction is observed. Anaprilin reduces the sensitivity of adrenoreceptor cells to adrenaline, providing a blockade.

It is this effect of the drug that promotes calm and reduces panic attacks. However, Anaprilin is not a sedative or a psychotropic drug. If VSD develops, it needs to neutralize the effects of adrenaline in a short time.

Anaprilin is absorbed at high speed and begins to act five minutes after administration if dissolved in the mouth. The greatest effect is achieved an hour after using the drug. The action continues for five hours. The medicine is sold in tablet form.

Alternative drugs

β-adrenergic receptors are located on the smooth muscles of the uterus. When they are excited, uterine contractions are inhibited. Thus, β-adrenergic receptors are involved in maintaining uterine tone.

Anaprilin should not be taken during pregnancy because the drug can cause blockade of receptors in the uterus. This leads to spontaneous pathological termination of pregnancy.

Therefore, you need to take drugs whose effect is similar to that of Anaprilin, but which do not affect the uterus in the same way. We can recommend Verapamil as an analogue of Anaprilin during pregnancy. Verapamil is one of the calcium channel blockers.

As you can see, Anaprilin, which is a non-selective β-blocker, is not indicated during pregnancy due to the negative effect on the fetus and uterine tone, which causes a serious threat of spontaneous termination of pregnancy (miscarriage or spontaneous abortion).

Girls, has anyone taken anaprilin?

Indications for the use of this drug are the following problems:

  • increased anxiety,
  • low pressure,
  • acute feeling of fear,
  • panic attacks, etc.

The main task of the drug:

  • blocking the work of beta-adrenergic receptors in various organs;
  • decrease in heart rate,
  • decreased conduction of nerve impulses,
  • lowering blood pressure,
  • reducing the heart's need for oxygen.

Anaprilin is a drug that is widely used in modern medicine as an antihypertensive drug - a medicine that lowers blood pressure. The drug is used for severe pathologies of the cardiovascular system - hypertension, arrhythmias and angina pectoris.

The drug effectively stops heart attacks, restoring a person’s well-being. However, the drug has a number of side effects. During pregnancy, anaprilin provides a systemic effect on the woman’s body, so it is not advisable to use it.

It is not allowed, if it is a β-blocker, then only a selective one so that it affects the heart. And anaprilin on the heart and uterus and bronchi

It is contraindicated. It increases the tone of the uterus, a β-blocker

I'm taking it now, but I'm not pregnant

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